Results 41 to 50 of about 391,404 (343)
Immunological recovery in patients with pulmonary tuberculosis after intensive phase treatment
Journal of International Medical Research, 2018 Objectives This study aimed to examine the change and significance of immune parameters in patients with sputum smear-positive pulmonary tuberculosis (TB) after 2 months of intensive phase anti-TB treatment.
Xuejiao Luo +4 more
doaj +1 more source
Frontiers in Immunology, 2019 The common gamma chain (γc) contributes to the formation of different cytokine receptors [e.g., IL-2 receptor (IL-2R), IL-7R, and IL-15R], which are important for generation of self-reactive T-cells in autoimmune diseases, like in type 1 diabetes (T1D ...
Julia Seyfarth +8 more
doaj +1 more source
Soluble IL-2Rα (sCD25) exacerbates autoimmunity and enhances the development of Th17 responses in mice. [PDF]
PLoS ONE, 2012 A strong association exists between mutations at the IL2 receptor alpha chain (CD25) gene locus and susceptibility to a number of T cell driven autoimmune diseases.
Shane E Russell +3 more
doaj +1 more source
RAGE Signaling in Skeletal Biology [PDF]
, 2019 PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M. +2 more
core +2 more sources
Important Role of the IL-32 Inflammatory Network in the Host Response against Viral Infection
Viruses, 2015 The pro-inflammatory cytokine interleukin (IL)-32 has gained much attention recently because of its important role in the inflammatory network. Since the discovery of IL-32 in 2005, our appreciation for its diverse roles continues to grow. Recent studies
Yaqin Zhou, Ying Zhu
doaj +1 more source
Cytokine units of immunoregulation of diabetic-associated osteoarthritis
Клінічна та профілактична медицина, 2020 Joint damage in patients with diabetes mellitus (DM) is a common complication and is associated with the induction of metabolic inflammation against the background of increased catabolic processes in various joint structures.
V.L. Orlenko
doaj +1 more source
Gene transfer of a soluble IL-1 type 2 receptor-Ig fusion protein improves cardiac allograft survival in rats [PDF]
, 2017 Objective: Interleukin-1 (IL-1) mediates ischemia-reperfusion injury and graft inflammation after heart transplantation. IL-1 affects target cells through two distinct types of transmembrane receptors, type-1 receptor (IL-1R1), which transduces the ...
Dudler, Jean +7 more
core
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Physiological Reports, 2019 Background The immune system generates inflammatory responses through cytokines like Interleukin 6 (IL‐6) and the Tumor Necrosis Factor alpha (TNF α); these cytokines mediate cellular responses aided by the presence of soluble receptors such as: Soluble ...
Henry H. León‐Ariza +3 more
doaj +1 more source
Activated γδ T cells inhibit osteoclast differentiation and resorptive activity in vitro [PDF]
, 2013 Peer reviewedPublisher ...
Pappalardo, A., Thompson, K.
core +1 more source