Results 91 to 100 of about 174,072,709 (188)

Serum levels of sST2 and CCL19 and their clinical significance in patients with psoriasis vulgaris at the progressive stage

Pifu-xingbing zhenliaoxue zazhi
[Objective] To investigate the serum levels of soluble suppression of tumorigenicity 2 (sST2) and C-C chemokine ligand 19 (CCL19) in patients with psoriasis vulgaris (PV) at the progressive stage and their clinical significance.
LI Shu, DING Weifang, HU Yaogang, CAO Dayong   +3 more
doaj   +1 more source

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci, Cansu Ozbayer, Ata Ozen, Gamze Zengin, Hulyam Kurt   +4 more
wiley   +1 more source

HUBUNGAN KADAR SOLUBLE SUPPRESSION OF TUMORIGENICITY 2 DENGAN FRAKSI EJEKSI VENTRIKEL KIRI PADA PENDERITA GAGAL JANTUNG KRONIK

, 2014
Latar Belakang: Gagal jantung kronik didefinisikan sebagai abnormalitas struktur dan fungsi jantung yang menimbulkan kehilangan fungsi miokard. Soluble suppression of tumorigenivity 2 (sST2) merupakan penanda yang dilepaskan oleh miosit jantung akibat
Desiekawati, Desiekawati
core   +1 more source

Somatic gene therapy for cancer. The utility of transferrinfection in generating ‘tumor vaccines’ [PDF]

, 1993
The last few years have seen the development of a branch of somatic gene therapy which aims at strengthening the immune surveillance of the body, leading to eradication of disseminated cancer tumor cells and occult micrometastases after surgical removal ...
Zatloukal, Kurt, Stingl, Georg, Schmidt, Walter, Cotten, Matthew, Wagner, Ernst, Birnstiel, Max L., Cotten, Matt   +6 more
core   +1 more source

Soluble suppression of tumorigenicity 2 levels are not predictive of non-AIDS events during antiretroviral therapy-mediated viral suppression

AIDS, 2019
: Before initiation of antiretroviral therapy (ART), levels of soluble suppression of tumorigenicity 2 (sST2) were not elevated in people living with HIV who later developed non-AIDS events (including myocardial infarction and stroke), compared with controls.
Alexis, Kay, Carlee, Moser, Ashley, McKhann, Milenka, Vargas, Magali, Porrachia, Sara, Gianella, Martin, Hoenigl   +6 more
openaire   +3 more sources

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Splenic CD8(+) T cells secrete TGF-beta 1 to exert suppression in mice with anterior chamber-associated immune deviation [PDF]

, 2009
Background CD8(+) regulatory T cells (Treg) have been considered to be involved in a model of ocular-induced tolerance, known as anterior chamber-associated immune deviation (ACAID).
Hao He, Lin, X.M., Peizeng Yang, Jiang, L.Q., Hongyan Zhou, Aize Kijlstra, Liqiong Jiang, Huang, X.K., Yang, P.Z., He, H., Zhou, H.Y., Xiaomin Lin, Xiangkun Huang, Kijlstra, A.   +13 more
core   +1 more source

The clinicopathological implications of serum IL-33 and sST2 as cancer biomarkers: A narrative review

Journal of Oral Biology and Craniofacial Research
Background: Interleukin (IL)-33 and its receptor, soluble suppression of tumorigenicity 2 (sST2), are key players in the immune response and cancer biology.
Swetha Acharya, Usha Hegde, Anirudh B. Acharya   +2 more
doaj   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source