Results 51 to 60 of about 174,072,709 (188)

Level and correlations of soluble suppression of tumorigenicity 2 protein in heart failure and its relationship with clinical and paraclinical characteristics of patients [PDF]

, 2022
Aim. To establish the correlations of the soluble suppression of tumorigenicity 2 protein (sST2) and N-terminal pro-brain natriuretic peptide (NT-proBNP) with some clinical and paraclinical characteristics of patients with heart failure (HF).Material and
A. V. Budnevsky, T. A. Chernik, A. Ya. Kravchenko, R. E. Tokmachev, A. V. Kontsevaya   +4 more
core   +1 more source

STADE‐HF (sST2 As a help for management of HF): a pilot study

ESC Heart Failure, 2020
Aims Biomarkers are not recommended until now to guide the management of patients with heart failure (HF). Soluble suppression of tumorigenicity 2 (sST2) appears as a promising biomarker. The current study considered pre‐discharged sST2 values as a guide
Fabien Huet, Jean Nicoleau, Anne‐Marie Dupuy, Corentin Curinier, Cyril Breuker, Audrey Castet‐Nicolas, Manuela Lotierzo, Eran Kalmanovich, Laetitia Zerkowski, Mariama Akodad, Jérôme Adda, Audrey Agullo, Florence Leclercq, Jean‐Luc Pasquie, Pascal Battistella, Camille Roubille, Pierre Fesler, Grégoire Mercier, Guillaume Bourel, Jean‐Paul Cristol, François Roubille   +20 more
doaj   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Tumorigenicity-associated characteristics of human iPS cell lines [PDF]

, 2018
Human induced pluripotent stem cells (hiPSCs) represent promising raw materials of human cell-based therapeutic products (hCTPs). As undifferentiated hiPSCs exhibit intrinsic tumorigenicity properties that enable them to form teratomas, hCTPs containing ...
Hideki Tsutsumi (197290), Yoji Sato (164343), Akihiro Umezawa, Michiyo Nasu (5819729), Takuya Kuroda (164325), Takumi Miura (412321), Takao Hayakawa (214691), Satoshi Yasuda, Takuya Kuroda, Keiko Tano (169945), Keiko Tano, Takumi Miura, Akihiro Umezawa (2402), Hideki Tsutsumi, Shinji Kusakawa (164327), Satoko Matsuyama, Nozomi Takada, Akifumi Matsuyama (420978), Yoji Sato, Michiyo Nasu, Takao Hayakawa, Shinji Kusakawa, Nozomi Takada (158434), Satoshi Yasuda (164326), Satoko Matsuyama (5819726), Akifumi Matsuyama   +25 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Soluble ST2 as a Potential Biomarker for Risk Assessment of Pulmonary Hypertension in Patients Undergoing TAVR?

Life, 2022
Background: Severe aortic valve stenosis (AS) is associated with pulmonary hypertension (PH) and has been shown to limit patient survival. Soluble suppression of tumorigenicity-2 (sST2) is a cardiovascular biomarker that has proven to be an important ...
Elke Boxhammer, Moritz Mirna, Laura Bäz, Nina Bacher, Albert Topf, Brigitte Sipos, Marcus Franz, Daniel Kretzschmar, Uta C. Hoppe, Alexander Lauten, Michael Lichtenauer   +10 more
doaj   +1 more source

Prognostic value of serum HDAC2 and sST2 in occupational asthma patients

环境与职业医学
BackgroundSome occupational asthma patients have a high risk of poor prognosis, and early assessment and screening of the high-risk groups with poor prognosis are crucial.ObjectiveTo evaluate the prognostic value of serum histone deacetylase 2 (HDAC2 ...
Ruifeng FENG, Zhentao LIN, Zhongpeng YANG, Hongmin YANG   +3 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source