Results 191 to 200 of about 1,781,718 (260)

Rapid diagnostics for point-of-care quantification of soluble transferrin receptor. [PDF]

EBioMedicine, 2019
Srinivasan B, Finkelstein JL, O'Dell D, Erickson D, Mehta S.   +4 more
europepmc   +1 more source

Chemical and Biological Determinants of PEG‐Lipid Shedding From Therapeutic Nanoparticles

Small, Volume 22, Issue 58, 16 October 2026.
PEG‐lipids play a central role in governing lipid nanoparticle stability, targeting, and function. However, PEG‐lipids can “shed” from the nanoparticle surface in biological environments, with the extent and kinetics of shedding influenced by chemical and biological factors.
Ethan P. Cisneros, Aadya S. Wijesekera, Lisa R. Volpatti   +2 more
wiley   +1 more source

Aetiology‐Specific Pancreatic Enzyme Dose Requirements and Treatment Outcomes in Pancreatic Exocrine Insufficiency: The Multicentre EURO‐PEI Registry

United European Gastroenterology Journal, Volume 14, Issue 8, October 2026.
ABSTRACT Background Pancreatic exocrine insufficiency (PEI) is a maldigestion syndrome leading to symptoms and nutritional deficiencies. Prospective real‐world data on pancreatic enzyme replacement therapy (PERT) dose requirements across aetiologies are limited. Objective To define PERT dose requirements and treatment outcomes across PEI aetiologies in
J. Enrique Domínguez‐Muñoz, Yessica Domínguez‐Novoa, Xurxo Martínez‐Seara, Peter Hegyi, Vinciane Rebours, Mary E. Phillips, Federico Bolado, Gabriele Capurso, Giulia de Marchi, Keith J. Roberts, Orsolya Eperjesi, Sandra Salmeron, David Ruiz‐Clavijo, Gaetano Lauri, Alessandro Brillo, Sarah Powell‐Brett, Jose Lariño‐Noia, Julio Iglesias‐García   +17 more
wiley   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, Volume 7, Issue 5, October 2026.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Dapagliflozin Attenuates NKCC2 Protein Expression and Alleviates Diabetic Kidney Disease in Salt Loaded‐Hypertensive Diabetic Db/Db Mice

FASEB BioAdvances, Volume 8, Issue 10, October 2026.
In salt‐loaded, hypertensive diabetic db/db mice with diabetic kidney disease, dapagliflozin lowered blood pressure and reduced tubular and glomerular injury. Mechanistically, dapagliflozin increased cullin E3 ligase abundance, promoting degradation of NKCC2.
Zenab Shahzad, Niharika Bala, Arooba Illyas, Amir Kazory, Indra Chandrasekar, Abdel A. Alli   +5 more
wiley   +1 more source

Polypropylene Nanoplastic Exposure to Respiratory Epithelial Barrier‐On‐Chip and Interfacial Interactions With Human Serum Albumin

Allergy, Volume 81, Issue 10, Page 3488-3503, October 2026.
Exposure to 305 nm PP NPs significantly disrupts the airway barrier‐on‐chip, reducing TEER, suppressing ZO‐1/ACE2 expression, and triggering ROS‐mediated apoptosis. In biological media, PP NPs exhibit a biphasic adsorption pattern, leading to the formation of a protein corona that increases their size to 364 nm.
Omur Sert, Eyup Bilgi, Reyhan Coban, Pelin Saglam‐Metiner, Basar Dogan, Zeynep Imir‐Tekneci, Suleyman Selim Cinaroglu, Ozlem Goksel, Ceyda Oksel Karakus, Ozlem Yesil‐Celiktas   +9 more
wiley   +1 more source

Iron, Biofilm, and Colorectal Cancer: Mechanistic Insights Into Enterococcus faecalis Pathogenesis

APMIS, Volume 134, Issue 10, October 2026.
ABSTRACT Enterococcus faecalis is a commensal of the human gastrointestinal microbiota that has emerged as a successful opportunistic pathogen associated with persistent infections, antimicrobial resistance, and biofilm formation. Increasing evidence indicates that iron availability functions as a master environmental signal coordinating E.
Sibusiso Luthuli, Nathalie Scarpulla, Lorenzo Bertolino, Lulama Luthuli, Emanuele Durante‐Mangoni   +4 more
wiley   +1 more source

Response to Letter to the Editor: "Comment on "Serum Hepcidin and Soluble Transferrin Receptor in the Assessment of Iron Metabolism in Children on a Vegetarian Diet"". [PDF]

Biol Trace Elem Res, 2018
Ambroszkiewicz J, Klemarczyk W, Mazur J, Gajewska J, Rowicka G, Strucińska M, Chełchowska M.   +6 more
europepmc   +1 more source

High Uric Acid Promotes Stem Leydig Cell Senescence by CCDC90B Mediates Mitochondrial Quality Control Imbalance

Cell Proliferation, Volume 59, Issue 10, October 2026.
In hyperuricemia, uric acid inhibits CCDC90B ubiquitination degradation by binding to it. Excessive CCDC90B induces mitochondrial calcium overload, leading to mitochondrial quality control imbalance and ultimately resulting in SLC senescence and decreased testosterone levels.
Jiayu Huang, Ao Wang, Xiangyu Li, Peng Huang, Kaixuan Zeng, Lu Sun, Moxuan Li, Yixiang Chen, Jiancheng Wang   +8 more
wiley   +1 more source

Comment on "Serum Hepcidin and Soluble Transferrin Receptor in the Assessment of Iron Metabolism in Children on a Vegetarian Diet". [PDF]

Biol Trace Elem Res, 2018
Rzymski P, Ganz T.
europepmc   +1 more source