Results 41 to 50 of about 6,130,460 (309)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Optimal solution of nonlinear equations [PDF]

open access: yes, 1985
journal articleWe survey recent worst case complexity results for the solution of nonlinear equations. Notes on worst and average case analysis of iterative algorithms and a bibliography of the subject are also ...
Optimal solution; Nonlinear equations   +1 more
core  

Skin autofluorescence is associated with glycemic variability in type 2 diabetes patients

open access: yesScientific Reports
Type 2 diabetes mellitus (T2DM) is a chronic disorder characterized by insulin resistance and hyperglycemia. To prevent diabetic complications, blood glucose levels should be maintained within a target range.
Eui Seok Shin   +4 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Numerical Study of Bending Behavior for 66 kV Submarine Cables

open access: yes한국해양공학회지
Submarine cables operate in complex marine environments and are repeatedly subjected to lateral loads from ocean currents, waves, and seabed irregularities.
YunJae Kim   +4 more
doaj   +1 more source

Unlocking European Grid Local Flexibility Through Augmented Energy Conversion Capabilities at District Level

open access: yesProceedings, 2017
Pentagon is research and innovation project that investigate the potential of wider deployment of energy conversion technologies and strategies at district-level, with the aim to foster flexibility in the low-voltage and medium-voltage grid. Multi-vector
Marco Rocchetti   +2 more
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Does digital cognitive behavioral therapy improve the insomnia and depression of workers to healthy levels? An open trial

open access: yesBioPsychoSocial Medicine
Background Cognitive behavioral therapy for insomnia (CBT-I) has a high potential for improving insomnia and depressive symptoms; however, it is unclear whether the improvement of symptoms reaches the level of healthy people without these symptoms.
Isa Okajima   +5 more
doaj   +1 more source

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