Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng +11 more
wiley +1 more source
Characterization of the Interaction between Human α<sub>1</sub>‑Acid Glycoprotein and Apremilast Enantiomers: HPLC, Isothermal Titration Calorimetry, Ultracentrifugation, and Docking Studies. [PDF]
Dombi G +9 more
europepmc +1 more source
Unveiling a Bulk WTaV Multicomponent Alloy With Superior Thermal Properties and Manufacturability
ABSTRACT Many tungsten (W)‐based medium and high entropy alloys (HEA) demonstrate superior microstructural stability and enhanced mechanical properties as compared to pure W, effectively rendering them as viable candidate materials for extreme environments such as nuclear fusion, aerospace applications, and so on.
Ishtiaque K. Robin +11 more
wiley +1 more source
Dynamics of Ferroelastic Domain Walls Associated with the Dielectric Relaxation in CsPbCl<sub>3</sub> Single Crystals. [PDF]
Yu Z, Zou C, Yang D.
europepmc +1 more source
Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan +15 more
wiley +1 more source
Valorization of Plant Biomass Through the Synthesis of Lignin-Based Hydrogels for Drug Delivery. [PDF]
Cárdenas-Vargas N +8 more
europepmc +1 more source
Breaking the Toughness‐Stretchability Trade‐Off in Hydrogels with Dynamic Hydrogen Bonding
A novel nanocomposite hydrogel architecture overcomes the inherent conflict between toughness and stretchability by integrating uniformly dispersed aminopropyl‐hybrid‐phyllosilicate nanosheets within a polyacrylamide matrix. This design leverages a dynamic hydrogen‐bonding network to facilitate efficient energy dissipation and self‐recovery.
Yining Gao +3 more
wiley +1 more source
A Green Innovative Approach for Solubility Enhancement of Poorly Water-Soluble Drugs Using Choline Chloride-Polyol Eutectic Solvents. [PDF]
Petersone L +3 more
europepmc +1 more source
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng +8 more
wiley +1 more source
Estimation of walking energy expenditure using a single sacrum-mounted IMU based on biomechanically-informed machine learning. [PDF]
Jung J +5 more
europepmc +1 more source

