Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
New aid architecture and resilience building around the Syria crisis
The international community has been piloting an integrated humanitarian, development and government response to the crisis in the region of Syria.
Gustavo Gonzalez
doaj
Developing Improvement Solutions for Evaluation System of the Iranian Maternal Health Program: A Qualitative Study [PDF]
Background and Objectives: Maternal health program is one of main domains of the primary health care worldwide. Considering the identified problems in evaluation system of the Iranian maternal health program, this study was conducted to develop ...
Rozita Firooznia +3 more
doaj
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
A new approach to old problems: the Solutions Alliance
Over the last three years, the Solutions Alliance has gradually emerged as a multi-stakeholder initiative to overcome the so-called humanitarian-development divide.
Alexander Betts
doaj
On the Solution of the Form Factor in Coupled Multi-Channel Problem [PDF]
Y. Iwamura +2 more
openalex +1 more source
Study on the free corrosion potential at an interface between an Al electrode and an acidic aqueous NaCl solution through density functional theory combined with the reference interaction site model [PDF]
Koichi Kano +3 more
openalex +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Displacement and development solutions in Tanzania
Tanzania’s refugee integration could serve as a blueprint for expanding the framework of durable solutions globally.
Erol Kekic, Harrison Mseke
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

