Results 241 to 250 of about 12,546,934 (336)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Implementing sleep apnea care to improve positive airway pressure adherence here and across the pond. [PDF]

Am J Respir Crit Care Med
Sathyapala SA, Parthasarathy S.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Constraints as catalysts: a model of emotional intelligence, team learning, and team resilience, in driving creativity and innovation. [PDF]

Front Psychol
Yesuf YM, Fields Z.
europepmc   +1 more source

Mercury vapor generation using a non-equilibrium cold atmospheric plasma jet for mercury determination equipped with atomic absorption spectrometry. [PDF]

RSC Adv
Akutsu K, Tanaka YK, Osawa T, Fukuchi K, Matsumura Y, Okino A, Ogra Y.   +6 more
europepmc   +1 more source

Optimizing Hearing Rehabilitation in Chronic Otitis Media: An Expert Opinion on Early Integration of Bone Conduction Devices. [PDF]

J Audiol Otol
Snapp HA, Backous DD, Borja MM, Fanelli K, Hernández N, Herzog JA, Jaramillo R, Komori M, Kong K, Lenarz T, Oishi N, Ray J, Zawawi F, Hol MKS.   +13 more
europepmc   +1 more source

Adolescent-led Our Voice method to promote healthy and active lifestyles and environments in South Africa. [PDF]

PLOS Glob Public Health
Wayas FA, Matwa N, West S, King AC, Oni T, Lambert EV.   +5 more
europepmc   +1 more source

Modeling of the electrostatic field generated by horizontal current sources in a sea-ice-covered four-layer medium. [PDF]

Sci Rep
Chen X, Sun Z, Jiang C, Zhu K, Li M, Jiang R, Yang W, Yan K, Du Y.   +8 more
europepmc   +1 more source

Evaluating the utility of storage solutions to preserve nucleic acid integrity at ambient temperature in South Africa. [PDF]

Afr J Lab Med
Moshoma T, Gededzha MP, Mampeule N, Mayne E.   +3 more
europepmc   +1 more source