Results 71 to 80 of about 23,096 (258)

Controllability of a Singular Hybrid System

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2020
We consider the linear hybrid system with constant coefficients that is not resolved with respect to the derivative of the continuous component of the unknown function. In Russian literature such systems are also called discrete-continuous.
P.S. Petrenko
doaj   +1 more source

Linearity, Non-determinism and Solvability

open access: yes, 2010
International audienceWe study the notion of solvability in the resource calculus, an extension of the λ-calculus modelling resource consumption. Since this calculus is non-deterministic, two different notions of solvability arise, one optimistic ...
Rocca, Simona Ronchi Della   +1 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Solvability Theorems Involving Inf-Convex Functions [PDF]

open access: yes, 1995
This paper presents a unified theory on solvability of certain general systems of inequalities involving functions expressible as the pointwise infimum of convex functions.
Craven, B.D.   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

On the equivalence of discrete Sturm–Liouville problem with nonlocal boundary conditions to the algebraic eigenvalue problem

open access: yesLietuvos Matematikos Rinkinys, 2015
We consider the finite difference approximation of the second order Sturm–Liouville equation with nonlocal boundary conditions (NBC). We investigate the condition when the discrete Sturm–Liouville problem can be transformed to an algebraic eigenvalue ...
Jurij Novickij, Artūras Štikonas
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Absolute Value Equation Solution via Dual Complementarity [PDF]

open access: yes, 2011
By utilizing a dual complementarity condition, we propose an iterative method for solving the NPhard absolute value equation (AVE): Ax?|x| = b, where A is an n n square matrix.
Mangasarian, Olvi
core  

Solvability of (max,+) and (min,+)-equation systems [PDF]

open access: yes
summary:Properties of (max,+)-linear and (min,+)-linear equation systems are used to study solvability of the systems. Solvability conditions of the systems are investigated. Both one-sided and two-sided systems are studied.
Zimmermann, Karel
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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