Results 91 to 100 of about 3,531,259 (296)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A Note on Solvable Polynomial Algebras [PDF]

open access: yesComputer Science Journal of Moldova, 2014
In terms of their defining relations, solvable polynomial algebras introduced by Kandri-Rody and Weispfenning [J. Symbolic Comput., 9(1990)] are characterized by employing Gr\"obner bases of ideals in free algebras, thereby solvable polynomial ...
Huishi Li
doaj  

Solvable Lie A-algebras

open access: yesJournal of Algebra, 2011
A finite-dimensional Lie algebra $L$ over a field $F$ is called an $A$-algebra if all of its nilpotent subalgebras are abelian. This is analogous to the concept of an $A$-group: a finite group with the property that all of its Sylow subgroups are abelian. These groups were first studied in the 1940s by Philip Hall, and are still studied today.
openaire   +3 more sources

The Byzantine Generals Problem

open access: yesACM Transactions on Programming Languages and Systems, 1982
Reliable computer systems must handle malfunctioning components that give conflicting information to different parts of the system. This situation can be expressed abstractly in terms of a group of generals of the Byzantine army camped with their troops ...
L. Lamport, R. Shostak, M. Pease
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Bethe Ansatz Solutions to Quasi Exactly Solvable Difference Equations

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2009
Bethe ansatz formulation is presented for several explicit examples of quasi exactly solvable difference equations of one degree of freedom which are introduced recently by one of the present authors.
Ryu Sasaki, Wen-Li Yang, Yao-Zhong Zhang
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Solvable self-dual impurity models

open access: yesJournal of High Energy Physics, 2019
We find a family of (half) self-dual impurity models such that the self-dual (BPS) sector is exactly solvable, for any spatial distribution of the impurity, both in the topologically trivial case and for kink (or antikink) configurations.
C. Adam   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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