Results 81 to 90 of about 3,560,062 (313)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Skeleton of matrix-product-state-solvable models connecting topological phases of matter

Physical Review Research, 2021
Models whose ground states can be written as an exact matrix-product state (MPS) provide valuable insights into phases of matter. While MPS-solvable models are typically studied as isolated points in a phase diagram, they can belong to a connected ...
Nick G. Jones, Julian Bibo, Bernhard Jobst, Frank Pollmann, Adam Smith, Ruben Verresen   +5 more
doaj   +1 more source

Classification of symmetry enriched topological phases with exactly solvable models [PDF]

, 2012
Recently a new class of quantum phases of matter: symmetry protected topological states, such as topological insulators, attracted much attention. In presence of interactions, group cohomology provides a classification of these [X.
A. Mesaros, Ying Ran
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Solvability of Graph Inequalities [PDF]

SIAM Journal on Discrete Mathematics, 2005
We investigate a new type of graph inequality (in the tradition of Cvetkovic and Simic [Contributions to Graph Theory and Its Applications, Technische Hochschule Ilmenau, Ilmenau, Germany, 1977, pp. 40--56] and Capobianco [Ann. New York Acad. Sci., 319 (1979), pp. 114--118]) which is based on the subgraph relation and which allows as terms fixed graphs,
Marcus Schaefer 0001, Daniel Stefankovic
openaire   +1 more source

Classification of solvable Leibniz algebras with null-filiform nilradical [PDF]

, 2012
In this article we classify solvable Leibniz algebras whose nilradical is a null-filiform algebra. We extend the obtained classification to the case when the solvable Leibniz algebra is decomposed as a direct sum of its nilradical, which is a direct sum ...
J. Casas, M. Ladra, B. Omirov, I. Karimjanov   +3 more
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source