Results 41 to 50 of about 2,673 (255)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
ON SOLVABILITY OF ONE DIFFERENCE EQUATION
Issues of Analysis, 2017 We consider a system of difference equation similar to those that appear as description of cumulative sums. Using Hamel bases, we construct pathological solutions to this system for constant right-hand sides. Also we show that bounded so- lutions do not exist for non-zero right-hand sides, while only constants can be solutions in the homogeneous case.
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Second order q-difference equations solvable by factorization method
Journal of Computational and Applied Mathematics, 2006 By solving an infinite nonlinear system of $q$-difference equations one constructs a chain of $q$-difference operators. The eigenproblems for the chain are solved and some applications, including the one related to $q$-Hahn orthogonal polynomials, are discussed.
Dobrogowska, Alina, Odzijewicz, Anatol
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Solvability of a Second Order Nonlinear Neutral Delay Difference Equation [PDF]
Abstract and Applied Analysis, 2011 This paper studies the second‐order nonlinear neutral delay difference equation , n ≥ n0. By means of the Krasnoselskii and Schauder fixed point theorem and some new techniques, we get the existence results of uncountably many bounded nonoscillatory, positive, and negative solutions for the equation, respectively.
Zeqing Liu +3 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
On an extension of a recurrent relation from combinatorics
Electronic Journal of Qualitative Theory of Differential Equations, 2017 The following recurrent relation/partial difference equation $$w_{n,k}=aw_{n-1,k-1}+bw_{n-1,k},$$ where $k,n,a,b\in\mathbb{N}$, appears in a problem in combinatorics. Here we show that an extension of the recurrent relation is solvable on, the, so called,
Stevo Stevic
doaj +1 more source
Solvability of a Higher-Order Nonlinear Neutral Delay Difference Equation [PDF]
Advances in Difference Equations, 2010 The authors consider the nonlinear neutral delay difference equation \[ \Delta(a_{kn}\cdots\Delta(a_{2n}\Delta(a_{1n}\Delta(x_n+b_n x_{n-d})))) +f(n,x_{n-r_{1n}},x_{n-r_{2n}},\dots,x_{n-r_{sn}})=0,\quad n\geq n_0, \] where \(d,k,s\in\mathbb{N}\), \(a_i,b\) are real sequences, \(r_{jn}\) are integers, and \(f:\{n_0,n_0+1,\dots\}\times\mathbb{R}^s\to ...
Liu Min, Guo Zhenyu
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