Results 81 to 90 of about 116,152 (330)

Solvable intransitive permutation groups with constant movement [PDF]

open access: yesJournal of Mahani Mathematical Research
In this paper, all solvable intransitive permutation groups with constant movement are classified and we show that they are one of the following groups: a cyclic $p$-group, an elementary abelian $p$-group, a Frobenius group of order 12 or a Frobenius ...
Mehdi Rezaei   +2 more
doaj   +1 more source

Solving Coupled Differential Equation Groups Using PINO-CDE [PDF]

open access: green, 2022
Wenhao Ding   +4 more
openalex   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Universal Deformation Formulae for Three-Dimensional Solvable Lie groups

open access: yes, 2003
We apply methods from strict quantization of solvable symmetric spaces to obtain universal deformation formulae for actions of every three-dimensional solvable Lie group. We also study compatible co-products by generalizing the notion of smash product in
Bieliavsky, Pierre   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

From homogeneous metric spaces to Lie groups

open access: yesComptes Rendus. Mathématique
We study homogeneous metric spaces, by which we mean connected, locally compact metric spaces whose isometry group acts transitively.After a review of a number of classical results, we use the Gleason–Iwasawa–Montgomery–Yamabe–Zippin structure theory to ...
Cowling, Michael G.   +4 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Discrete group method for a mathematical model of the diffusion in swelling gelatin

open access: yesMathematical Modelling and Analysis
In this article, we will introduce the mathematical model of the diffusion process in a swelling medium that has already been modeled. The main purpose of this paper is introducing a new class of group transformations for solving the nonlinear emulsion ...
Parviz Darania
doaj   +1 more source

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