Results 101 to 110 of about 116,152 (330)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Efficient Preparation of Solvable Anyons with Adaptive Quantum Circuits
Physical Review XThe classification of topological phases of matter is a fundamental challenge in quantum many-body physics, with applications to quantum technology. Recently, this classification has been extended to the setting of adaptive finite-depth local unitary ...
Yuanjie Ren +2 more
doaj +1 more source
The K-theory ranks for crossed products of C*-algebras by the group of integers
Cubo, 2019 We study the K-theory ranks for crossed products of C∗-algebras by the group of integers. As an application, we obtain certain estimates for the K-theory ranks of the group C∗-algebras of torsion free, finitely generated, nilpotent or solvable discrete ...
Takahiro Sudo
doaj +1 more source
On a New Criterion for the Solvability of Non-Simple Finite Groups and m-Abelian Solvability [PDF]
, 2021 Hasan Sankari, Mohammad Abobala
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Solving the conjugacy problem in Garside groups by cyclic sliding [PDF]
, 2008 Volker Gebhardt, Juan González-Meneses
openalex +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
The Herzog-Schönheim conjecture for solvable groups [PDF]
, 2019 Michael C. Burkhart
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Regular orbits of finite primitive solvable groups, the final classification [PDF]
, 2022 Derek F. Holt, Yong Yang
openalex +1 more source