Results 1 to 10 of about 10,193 (263)

Unlocking Niclosamide Solid Forms via Mechanochemistry: Discovery of a 2-Pyrrolidone Solvate. [PDF]

Pharmaceutics
Background/Objectives: Niclosamide, an anthelmintic drug included in the World Health Organization Model List of Essential Medicines, has recently attracted attention for drug repurposing applications.
D'Abbrunzo I, Rizzetto V, Gigli L, Demitri N, Argentieri F, Stener M, Passerini N, Perissutti B.   +7 more
europepmc   +2 more sources

Crystal structure of nicotinamide ethyl-ene glycol hemisolvate. [PDF]

Acta Crystallogr E Crystallogr Commun
In the title solvate, C6H6N2O·0.5C2H6O2, the asymmetric unit consists of one nicotinamide molecule and half of an ethylene glycol molecule, which is completed by crystallographic inversion symmetry.
Chunanant T, Rapeenun P, Lertna N, Flood AE.   +3 more
europepmc   +2 more sources

Crystal Structure, Stability and Desolvation of the Solvates of Sorafenib Tosylate

Crystals, 2019
In this study, three solvates of sorafenib tosylate were obtained from methanol, ethanol and n-methyl-2-pyrrolidone (NMP) after solvate screening and the effect of solvent on the formation of solvate was analyzed. The solvents with high value of polarity/
Lina Jia, Junbo Gong, Shichao Du
exaly   +3 more sources

Maleate salts of bedaquiline

Acta Crystallographica Section E: Crystallographic Communications, 2021
Bedaquiline is one of two important new drugs for the treatment of drug-resistant tuberculosis (TB). It is marketed in the US as its fumarate salt, but only a few salts of bedaquiline have been structurally described so far.
Matthias Zeller, Susan Bogdanowich-Knipp, Pamela Smith, Dale K. Purcell, Mercy Okezue, Daniel T. Smith, Stephen R. Byrn, Kari L. Clase   +7 more
doaj   +1 more source

Halogen-Bonding-Driven Self-Assembly of Solvates of Tetrabromoterephthalic Acid

Crystals, 2021
Halogen bonding is one of the most interesting noncovalent attractions capable of self-assembly and recognition processes in both solution and solid phase.
Nucharee Chongboriboon, Kodchakorn Samakun, Winya Dungkaew, Filip Kielar, Mongkol Sukwattanasinitt, Kittipong Chainok   +5 more
doaj   +1 more source

meso-α,α-5,15-Bis(o-nicotinamidophenyl)-10,20-diphenylporphyrin n-hexane monosolvate

IUCrData, 2023
The structure of the title solvated porphyrin, C56H38N8O2·C6H14, is reported. Two porphyrin molecules, one ordered and one disordered n-hexane solvate molecules are present in its asymmetric unit.
Xiaotao Sun, Jianfeng Li
doaj   +1 more source

Crystallization Selectivity of Ribavirin Solution and Amorphous Phase

Molecules, 2023
Crystallization selectivity is an important principle in polymorph control. Ribavirin Form I, Form II, DMSO solvate, and amorphous ribavirin are prepared, and the short-range order similarities between these solid forms and ribavirin aqueous solution and
Fuying Li, Shiying Chen, Haoxin Hu, Chengfeng Liang, Shiyu Sun, Can Jin, Fenghua Chen   +6 more
doaj   +1 more source

Hidden Solvates and Transient Forms of Trimesic Acid

Crystals, 2020
This article discusses the formation of trimesic acid (TMA) solvates with ethanol, isopropyl alcohol and dimethylformamide via liquid-assisted grinding and slurry experiments.
Martin R. Ward, Iain D. H. Oswald
doaj   +1 more source

The Relevance of Lithium Salt Solvate Crystals in Superconcentrated Electrolytes in Lithium Batteries

Energies, 2023
Based on the unique ubiquity of similar solvate structures found in solvate crystals and superconcentrated electrolytes, we performed a systematic study of four reported solvate crystals which consist of different lithium salts (i.e., LiMPSA, LiTFSI ...
Jake A. Klorman, Kah Chun Lau
doaj   +1 more source

2,5,8,11-Tetramethyl-2,5,8,11-tetraazadodecane-2,11-diium bis[hydroxytris(pentafluorophenyl)borate] benzene 2.5-solvate

IUCrData, 2022
The title compound of overall stoichiometry, C12H32N42+·2C18HBF15O−·2.5C6H6, crystallizes in the triclinic space group P\overline{1} and the stoichiometry of the asymmetric unit consists of two [C12H32N4]2+ dications, two [C18HBF15O]− anions, and 2.5 ...
Ray J. Butcher, Andrew P. Purdy
doaj   +1 more source