Results 21 to 30 of about 65,658 (300)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Legal regulation of insurance companies' solvency in the EU: Solvency II [PDF]
The improvement of science and practice of risk management, the development of the insurance market, an increasing importance of the insurance industry and the introduction of Basel II regulations in the banking industry, have led to the development of ...
Njegomir Vladimir, Petrović Zdravko
doaj
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
SOLVENCY II – THE NEW EU SOLVENCY REGIME ON THE INSURANCE MARKET [PDF]
The main causes that lead to insurer’s solvency issues such as the underwriting, investment or reinsurance deficiencies have remained the same over time. However, their incidence is increasing, as well as their complexity.
Emilia CLIPICI
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Quantitative Market Risk Assessment for Insurance Companies
The business strategy, the underwriting policy, the investment strategy of insurance companies and some external factors influence their ability to meet liabilities.
E. V. Aldukhova
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
THE IMPACT OF TRANSITION FROM SOLVENCY I TO SOLVENCY II OVER THE PREMIUM RESERVES IN GENERAL INSURANCE [PDF]
One of the most important purposes of any insurance company is to be solvable. The technical reserve represents the main part of the obligations of an insurance company, thus the correct evaluation of this item is primordial.
Oleg VEREJAN, Victor CALDARE
doaj
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The main purpose of this paper is to analyze Solvency II which is a new supranational insurance regulatory regime introduced by the institutions of the European Union in order to enhance the financial stability of the insurance and reinsurance ...
Biljana Petrevska
doaj

