Results 31 to 40 of about 65,658 (300)

System of governance in insurance companies according to directive 'Solvency II' [PDF]

open access: yesStrani pravni život, 2018
The author of this article examines the system of governance in insurance companies according to new regulatory regime 'Directive Solvency II' which entered into force in the European Union on 1 January 2016.
Leković Vuk
doaj  

The problem of legislative regulation of outsourcing in the insurance industry

open access: yesУченые записки Российской академии предпринимательства, 2021
The article is analyzed the Russian and foreign experience of legal regulations of outsourcing in the insurance industry, as well as proposed of recommendations for improvement legislative regulation.
M. A. Fedorov
doaj  

Solventnost II in holistično obvladovanje tveganj

open access: yesEconomic and Business Review, 2017
The Solvency II Directive poses a major challenge to insurance companies, fundamentally changing the way they currently do business. In the study, we examined the qualitative requirements of the so-called second pillar, namely the role, importance and ...
Helena Bešter
doaj   +1 more source

A market-consistent framework for the fair evaluation of insurance contracts under Solvency II [PDF]

open access: yes, 2019
The entry into force of the Solvency II regulatory regime is pushing insurance companies in engaging into market consistence evaluation of their balance sheet, mainly with reference to financial options and guarantees embedded in life with-profit funds ...
Casalini, R.   +3 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Surrender Risk in the Context of the Quantitative Assessment of Participating Life Insurance Contracts under Solvency II

open access: yesRisks, 2018
Participating life insurance contracts entitle the policyholder to participate in the company’s annual surplus. Typically, they are also equipped with a surrender option that allows the policyholder to terminate the contract prior to maturity ...
Tobias Burkhart
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

"A correlation sensitivity analysis of non-life underwriting risk in solvency capital requirement estimation" [PDF]

open access: yes
This paper analyses the impact of using different correlation assumptions between lines of business when estimating the risk-based capital reserve, the Solvency Capital Requirement (SCR), under Solvency II regulations.
Antoni Ferri   +2 more
core   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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