Results 61 to 70 of about 57,709 (348)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

ANALISIS LAPORAN KEUANGAN DARI TAHUN 2013-2015 PADA KOPERASI KARTIKA D-10/GABUNGAN AJEN KOREM 074/WARASTRATAMA SURAKARTA

Jurnal Kewirausahaan dan Bisnis, 2017
The purpose of the study is to determine the financial performance of the Cooperative Kartika D-10/Gabungan Ajen Korem 074 Warastrama Surakarta in the period of 2013-2015 in terms of the ratios of liquidity, solvency, and profitability.
Budi Joko Santosa
doaj   +1 more source

Calculation of Liquidity, Solvency and Profitability Ratio in Manufacturing Company

Journal of Applied Accounting and Taxation, 2018
This research discuss the calculation of liquidity, solvency and profitability ratios. The liquidity ratio is the ratio that describes the company's ability to meet short-term liabilities, solvency ratio is the ratio that describes the company's ability to meet long-term obligations and the profitability ratio is the ratio that measures the company's ...
Shinta Wahyu Hati, Rally Ferry Agusta
openaire   +2 more sources

Analisis Rasio Solvabilitas Pada PT Bank Sulut [PDF]

, 2014
: To cover the shortage of funds, the company will need to obtain funds from its own capital and of leadership. When combining these two sources of funds is called the ratio of borrowed funds or solvency ratio or leverage ratio, which recognizes the ...
kalesaran, C. N. (Christie), Keles, D. (Dantje), Pelleng, F. (Frendy)   +2 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Pengaruh Modal Asing Terhadap Kinerja Keuangan (Studi Kasus Pada PT. Karya Mandiri Di Bandar Lampung) [PDF]

, 2011
The purpose of this study was to determine the effect of increasing foreign equity to the level of liquidity, solvency and profitability of the company and to determine the trend of the use of foreign capital and the development of liquidity, solvency ...
Habiburrahman, H. (Habiburrahman), Haninun, H. (Haninun), Laksana, P. A. (Panji)   +2 more
core  

Expansion of the current methodology for the study of the short-term liquidity problems in a sector [PDF]

, 2018
Purpose: The aim of this work consists of defining and applying a new methodology for the calculation of short-term financial ratios that more reliably approximate the solvency of a sector.
Farreras Noguer, Maria Àngels, Linares Mustarós, Salvador, Rondós Casas, Elena   +2 more
core   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Analisis Kinerja Keuangan PT Grahamas Citrawisata Tbk the Hills Bukittinggi Hotel and Convention Periode 2009-2013 [PDF]

, 2016
The purpose of this study are to knowing financial performance PT. Grahamas Citrawisata Tbk 2009-2013 period from liquidity side, solvency side, activity side, profitability side of the company.
Abrian, Y. (Youmil), Wanara, A. D. (Anangga), Yuliana, Y. (Yuliana)   +2 more
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source