Plasticizer-Enabled Solvent-Free Curing of Self-Healing Binder System for Energetic Materials. [PDF]
Zhang M +9 more
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
High-Accuracy Quantitative Nuclear Magnetic Resonance Using Improved Solvent Suppression Schemes. [PDF]
Garrido BC +3 more
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Understanding and Controlling the Colloidal Stability of CdSe Nanoplatelets by Solvation Force Engineering. [PDF]
Chen S +4 more
europepmc +1 more source
The Influence of the Solvent on Reaction Velocity. III. The Hydrolysis of Valerolactone. [PDF]
Eero Tommila +5 more
openalex +1 more source
Solvents, Ionic Liquids and Solvent Effects [PDF]
Daniel Glossman-Mitnik +1 more
openaire +2 more sources
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
<sup>19</sup>F NMR-based solvent accessibility profiling reveals tryptophan ring-flip dynamics in a protein. [PDF]
Kawagoe S, Kumeta H, Saio T.
europepmc +1 more source

