Results 191 to 200 of about 770,570 (268)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Methanol-Regulated Interfacial Polymerization of Fluorinated Polyamide Membranes Enables Rapid Liquid Hydrocarbon Separation. [PDF]

Adv Sci (Weinh)
Li X, Yan M, Ma K, Li J, Huang Y, Liu W, He M, Wang X, Ma J, Zhou Z.   +9 more
europepmc   +1 more source

Programmable and sustainable scaling up of squaramide-based compounds through customizable paper-based platforms. [PDF]

RSC Adv
Kalligosfyri PM, Alfano AI, Cinti S, Brindisi M.   +3 more
europepmc   +1 more source

Quantum Chemical Microsolvation via Free Energy-Based Solvation Site Identification. [PDF]

J Chem Theory Comput
Magenheim LB, Podewitz M.
europepmc   +1 more source

Cytoprotective Evaluation of <i>Juglans regia</i> L. Septum Extract and Development of Extract-Based Gels and Films for Topical Application. [PDF]

Pharmaceutics
Luksiene J, Rimkiene L, Majiene D, Kazlauskaite JA, Bernatoniene J, Zevzikovaite N, Zevzikovas A.   +6 more
europepmc   +1 more source

The Electrosolvation Effect: The Medium Is the Message. [PDF]

Langmuir
Wang S, Behjatian A, Le A, Zhu X, Krishnan M.   +4 more
europepmc   +1 more source