Results 181 to 190 of about 770,570 (268)

Evidence for multi-Li⁺ clustering in lithium-ion battery electrolytes. [PDF]

Nature
Stevenson JM, Agarwal G, Debnath S, Goldsmith ZK, Mondal M, Svirinovsky-Arbeli A, Yeu IW, Metlay AS, Kwon Y, Bhai L, Guha RD, Keeler EG, Weber JL, Steingart DA, Marbella LE, Urban A, Jacobson LD, Halls MD, Friesner RA.   +18 more
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Comparative Evaluation of Pressurized Liquid and Conventional Solvent Extraction of Agro-Industrial By-Products: Phenolic and Flavonoid Contents, Antioxidant Capacity and Cytotoxicity Assessment. [PDF]

Foods
di Corcia ML, Luceri C, Bigagli E, Conte A, Del Nobile MA.   +4 more
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Single-component dual emission and full-spectrum color tuning from through-space charge transfer in asymmetric [2.2]paracyclophanes. [PDF]

Chem Sci
Hernandez Gomora KD, Jogi BR, Hadjipetkov P, Shumway J, Ahmad S, Moody H, Mumbaraddi D, Srimath Kandada AR, Schaack C.   +8 more
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Optimisation of the gelation process and performance characterisation of nitrogen-containing Guanylurea double-based explosive materials through rheological modelling and parameter coupling analysis. [PDF]

RSC Adv
Dong J, Dong J, Mao C, Duan Y, He X, Ji W.   +5 more
europepmc   +1 more source