Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Solvent Effects on the Blinking Statistics of Color Centers in Chemical Vapor Deposition-Grown hBN. [PDF]
Queirós T, Alpuim P, Nieder JB.
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Deciphering Molecular and Solvent Effects on Aqueous and Organic Solubility through Interpretable Machine Learning Approaches. [PDF]
Gopichand B +3 more
europepmc +1 more source
Solvent Effects in the Preparation of Catalysts Using Activated Carbon as a Carrier. [PDF]
Xu Z +8 more
europepmc +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Solvent Effects on the Photophysical Properties of Unexplored Imidazo[1,2‑<i>a</i>]pyridine Derivatives. [PDF]
Justino Garcia Praciano VH +4 more
europepmc +1 more source
Solvent Effects on the Elasticity of Electrospinnable Polymer Solutions. [PDF]
Ewaldz E, Randrup J, Brettmann B.
europepmc +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Disentangling solvent effects on optical response via p-π and sp² lone-pair contributions in non-aromatic fused systems. [PDF]
Ibrahim M +4 more
europepmc +1 more source

