Results 111 to 120 of about 486,719 (268)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Role of water in determining organic reactivity in aqueous binary solvents

Open Chemistry, 2012
Salmar Siim, Järv Jaak, Tenno Tiina, Tuulmets Ants   +3 more
doaj   +1 more source

Octahedral Zirconium Salan Catalysts for Olefin Polymerization: Substituent and Solvent Effects on Structure and Dynamics. [PDF]

Inorg Chem, 2023
Dall'Anese A, Kulyabin PS, Uborsky DV, Vittoria A, Ehm C, Cipullo R, Budzelaar PHM, Voskoboynikov AZ, Busico V, Tensi L, Macchioni A, Zuccaccia C.   +11 more
europepmc   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Decoding Solvent Effects in Electrocatalytic Biomass Valorization: Levulinic Acid to γ‑Valerolactone. [PDF]

ACS Sustain Chem Eng
Vilariño P, Bautista Q, Gómez E, Serrà A.   +3 more
europepmc   +1 more source

Antiradical Activity of Lignans from Cleistanthus sumatranus: Theoretical Insights into the Mechanism, Kinetics, and Solvent Effects. [PDF]

ACS Omega, 2023
Bay MV, Nam PC, Hoa NT, Mechler A, Vo QV.   +4 more
europepmc   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Spectroscopic, electrochemical, thermodynamic and theoretical insights into solvent effects for the intensification of the modified OxFA process. [PDF]

RSC Adv
Krueger JH, Saedi P, Poller MJ, Zaitsau DH, Siewert R, Robinson D, Müller K, Albert J.   +7 more
europepmc   +1 more source

Dissecting Solvent Effects on Hydrogen Bonding. [PDF]

Angew Chem Int Ed Engl, 2022
Meredith NY, Borsley S, Smolyar IV, Nichol GS, Baker CM, Ling KB, Cockroft SL.   +6 more
europepmc   +1 more source