Results 141 to 150 of about 644,240 (320)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Continuous liquid–liquid extraction to recover lignin and furanics from lactic acid:Choline chloride deep eutectic solvent after cooking of spruce [PDF]

open access: yes
Lactic acid: choline chloride mixed in a 10:1 ratio is known to be a suitable delignification solvent. This deep eutectic solvent (DES) can produce lignin and hemicellulose derivatives as byproducts to cellulose.
Gholami, Mahsa   +2 more
core   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

The Effect of Solvent Extraction of Light Lubricating Oil on Viscosity Index and Chemical Composition

open access: yesIraqi Journal of Chemical and Petroleum Engineering, 2007
An investigation was conducted for the improvement of viscosity index of light lubricating oil fraction (40 stock) obtained from vacuum distillation unit of lube oil plant of Daura Refinery, using solvent extraction process.
Abdul-Halim A.-K. Mohammed   +2 more
doaj  

Automated Microsolvation for Minimum Energy Path Construction in Solution [PDF]

open access: yesarXiv
Describing chemical reactions in solution on a molecular level is a challenging task due to the high mobility of weakly interacting solvent molecules which requires configurational sampling. For instance, polar and protic solvents can interact strongly with solutes and may interfere in reactions.
arxiv  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

The solvent extraction is a potential choice to recover asphalt from unconventional oil ores

open access: yesArabian Journal of Chemistry, 2023
The abundant unconventional oil ores (about 70% of total world oil) are playing an increasingly important role in global energy supply. To obtain asphalt in unconventional oil ores, different methods, including hot water-based extraction, pyrolysis and ...
Xiaoya Mu   +4 more
doaj  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

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