Results 61 to 70 of about 260,772 (289)
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Kinetics and thermodynamics of cottonseed oil extraction
Petroleum derived n-hexane is commercially used in solvent extraction plants due to its higher extraction efficiency in spite of the fact that it is graded as highly toxic and hazardous.
Devesh K. Saxena +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
To address the issues of high energy consumption and high carbon emissions associated with the steam injection development of ultra-heavy oil in China, technological exploration focusing on electrical heating and solvent substitution was conducted ...
Xinge Sun +7 more
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The thermodynamic contribution to extraction of medical devices by organic solvents as a first sample preparation step in chemical characterization studies is evaluated by Abraham's solvation parameter model using five representative materials (low ...
Jianwei Li
doaj +1 more source
Microalgae have the potential to produce a big amount of biodiesel per area unit owing to its high lipid content. However, for a sustainable biodiesel production from microalgae, the concept of biorefinery must be taken into account; this concept can be ...
Ángel Darío González-Delgado +1 more
doaj +1 more source
Solvent toxicity is of major concern in the extraction of lipid from algae biomass via the solvent extraction technique. This study was carried out to determine the optimal solvent mixture (chloroform, methanol, ethanol, and dichloromethane) composition ...
Sherif Ishola Mustapha +1 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

