Results 111 to 120 of about 101,675 (310)

Overcoming biomass recalcitrance by combining genetically modified switchgrass and cellulose solvent-based lignocellulose pretreatment.

open access: yesPLoS ONE, 2013
Decreasing lignin content of plant biomass by genetic engineering is believed to mitigate biomass recalcitrance and improve saccharification efficiency of plant biomass. In this study, we compared two different pretreatment methods (i.e., dilute acid and
Noppadon Sathitsuksanoh   +3 more
doaj   +1 more source

DNA unwinding component of the nonhistone chromatin proteins [PDF]

open access: yes, 1976
A subclass of nonhistone chromatin proteins from rat liver, previously shown to exhibit high affinity for DNA, has been fractionated by single-stranded DNA-agarose affinity chromatography.
Patel, Gordhan L., Thomas, Terry L.
core  

Bidimensional Tandem Mass Spectrometry for Selective Identification of Nitration Sites in Proteins. [PDF]

open access: yes, 2007
Nitration of protein tyrosine residues is very often regarded as a molecular signal of peroxynitrite formation during development, oxidative stress, and aging.
AMORESANO, ANGELA   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organic Solvent Recovery and Reuse in Pharmaceutical Purification Processes by Nanofiltration Membrane Cascades

open access: yesChemical Engineering Transactions, 2015
The recovery and posterior reuse of organic solvents is a very important aspect to be taken into account during the production processes by chemical, petrochemical, food, and pharmaceutical industries.
R. Abejon, A. Garea, A. Irabien
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Fractionation for Biodiesel Purification Using Supercritical Carbon Dioxide

open access: yesEnergies, 2014
In recent years, biodegradable and alternative biodiesel has attracted increased attention worldwide. Producing biodiesel from biomass involves critical separation and purification technology.
Chao-Yi Wei   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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