Results 231 to 240 of about 101,675 (310)

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Fractionation of Saffron (<i>Crocus sativus</i> L.) Extract by Solid-Phase Extraction and Subsequent Encapsulation in Liposomes Prepared by Reverse-Phase Evaporation. [PDF]

Molecules
Ruggieri F, Maggi MA, Commito F, Badia F, Giansanti L.   +4 more
europepmc   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Concluding remarks: <i>Faraday Discussion</i> on Frontiers in physical chemistry in lignin valorization.

Faraday Discuss
Barta K.
europepmc   +1 more source

Comparative Study of Fractionation Technologies and Their Impact on the Nutritional and Functional Properties of Maize and Rice Fractions. [PDF]

Food Bioproc Tech
Sukop U, Zettel V, Boyaciyan C, Schönlecher R, Höfler K, D'Amico S, Domig KJ, Bender D, Jekle M.   +8 more
europepmc   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Fractionation and Chemical Characterization of Cell-Bound Biosurfactants Produced by a Novel <i>Limosilactobacillus fermentum</i> Strain via Cheese Whey Valorization. [PDF]

Foods
Alimpoumpa D, Papapostolou H, Alexandri M, Kachrimanidou V, Kopsahelis N.   +4 more
europepmc   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Separation of α‑Terpineol and Limonene from an Orange Essential Oil Mixture Using Supercritical CO₂ Pressure Reduction. [PDF]

ACS Omega
de Melo RPF, Moreira RC, Pastore GM, Bicas JL, Martínez J, Dos Santos LC.   +5 more
europepmc   +1 more source

Dry fractionation of solvent-extracted castor meal

Industrial Crops and Products
Liv S. Severino, Fábio P. Silva, Maria E.C. Esquibel, Andressa S. Rocha   +3 more
openaire   +1 more source