Results 101 to 110 of about 813,308 (361)

Substrate Specificity of Peptide Adsorption: A Model Study

open access: yes, 2007
Applying the contact density chain-growth algorithm to lattice heteropolymers, we identify the conformational transitions of a nongrafted hydrophobic-polar heteropolymer with 103 residues in the vicinity of a polar, a hydrophobic, and a uniformly ...
L. Toma   +2 more
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Solvent Supercritical Fluid Technologies to Extract Bioactive Compounds from Natural Sources: A Review

open access: yesMolecules, 2017
Supercritical fluid technologies offer a propitious method for drug discovery from natural sources. Such methods require relatively short processing times, produce extracts with little or no organic co-solvent, and are able to extract bioactive molecules
K. Khaw, M. Parat, P. Shaw, J. Falconer
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Molecular Structure of Heterocycles: 6. Solvent Effects on the 17O Nmr Chemical Shifts of 5-Trichloromethylisoxazoles

open access: yesJournal of the Brazilian Chemical Society, 2001
A multilinear-regression analysis using the Kamlet-Abboud-Taft (KAT) solvatochromic parameters in order to elucidate and quantify the solvent effects on the 17O chemical shifts of three 5-trichloromethylisoxazoles [(1a) non-, (1b) 3-methyl- and (1c) 4 ...
Martins Marcos A. P.   +7 more
doaj  

Crosslinked polybenzimidazole membranes for organic solvent nanofiltration (OSN): Analysis of crosslinking reaction mechanism and effects of reaction parameters

open access: yes, 2015
Recently, polybenzimidazole (PBI) membranes crosslinked with dibromoxylene (DBX) were shown to retain their molecular separation performance in the harsh conditions characteristic of organic solvent nanofiltration (OSN).
Irina B. Valtcheva   +2 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Effects of Extraction Process Parameters on the Quality Characteristics of Parinari Polyandra B. Seed Oil

open access: yesNigerian Journal of Technological Development, 2016
Extraction process parameters can influence the quality of oil obtained from seeds during extraction process. The effect of extraction process parameters on the quality of parinari seed oil, a potential renewable industrial raw material, is yet to be ...
T. E. Odetoye   +2 more
doaj   +2 more sources

Investigating nano-structured domains within ionic liquids: the effect of cation change on thermal equilibrium and relaxation of spiropyran and spirooxazine. [PDF]

open access: yes, 2009
The established belief that ionic liquids (ILs) behave as homogenous solvents such as that observed in molecular solvents has been challenged.1, 2 Previous use of solvatochromic probe dyes has allowed for the traditional parameter of ‘polarity’ to be ...
Byrne, Robert   +2 more
core  

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