Results 241 to 250 of about 1,075,486 (337)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Excited-State Relaxation Pathways of 4-Aminobiphenyl-2-Pyrimidine Derivatives: An Ultrafast Perspective. [PDF]

J Phys Chem A
Cortés-Villena A, Gonzalez-Carrero S, Aliaga C, Domínguez M, Vidal M, Rojas P, Galian RE, Pérez-Prieto J.   +7 more
europepmc   +1 more source

LiBr-mediated, solvent free von Pechmann reaction: facile and efficient method for the synthesis of 2H-chromen-2-ones

, 2007
Sanjay Kumar, Anil Saini, Jagir S. Sandhu   +2 more
openalex   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Multisolvent metabolite profiling of coffee waste by UHPLC-HRMS/MS and molecular networking. [PDF]

Comput Struct Biotechnol J
Soontontaweesub S, Lertsuwan R, Pruksatrakul T, Paemaee A, Champreda V, Laosiripojana N.   +5 more
europepmc   +1 more source

Solvent solution.

Environmental Health Perspectives, 1997
openaire   +1 more source

Influence of N-donor bases and the solvent in oxodiperoxomolybdenum catalysed olefin epoxidation with hydrogen peroxide in ionic liquids

, 2011
Matthew Herbert, Francisco Montilla, Agustı́n Galindo, Raquel Moyano, Antonio Pastor, Eleuterio Álvarez   +5 more
openalex   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Theoretical insights into the dissolution of LiFSI in weakly and strongly solvating solvents. [PDF]

RSC Adv
Nyepetsi M, Mbaiwa F.
europepmc   +1 more source

Screening of functional solvent system for automatic aldehyde and ketone separation in aldol reaction: A combined COSMO-RS and experimental approach

, 2019
Chenyue Zhang, Zhen Song, Can Jin, Job Nijhuis, Teng Zhou, Timothy Noël, Harald Gröger, Kai Sundmacher, Jan C. M. van Hest, Volker Hessel   +9 more
openalex   +1 more source