Results 141 to 150 of about 195,697 (244)

Transport‐related effects on intrinsic and synaptic properties of human cortical neurons: A comparative study

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we investigated how transporting brain slices influences the electrophysiological and morphological properties of human cortical neurons. Whole‐cell patch‐clamp recordings were obtained from acute slices prepared from tissue collected during epilepsy or tumor surgeries, either on‐site or off‐site, after ...
Guanxiao Qi   +7 more
wiley   +1 more source

Amacrine cell inputs to OFF midget ganglion cells in macaque retina

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The goal of this study was to explain the findings from physiological studies that OFF midget ganglion cells had larger receptive field centers than expected from their dendritic field diameters. First, we confirmed that OFF mRGCs (OFF MGC) receive input from diffuse bipolar cells (DB) as well as OFF midget bipolar cells (FMB ...
David W. Marshak   +8 more
wiley   +1 more source

DACIT device for axon cancer cell interaction testing in 2D and 3D. [PDF]

open access: yesiScience
Velazquez-Quesada I   +9 more
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière   +6 more
wiley   +1 more source

Distinct developmental dynamics of opposing persistent currents shape motoneuron firing during motor maturation of zebrafish

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend During the first few days of development, zebrafish acquire the ability to produce increasingly refined movements that rely progressively less on the activity of primary motoneurons. At the same time, primary motoneurons undergo functional maturation, becoming increasingly capable of repetitive firing.
Stephanie F. Gaudreau, Tuan V. Bui
wiley   +1 more source

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