Results 171 to 180 of about 195,697 (244)
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun +15 more
wiley +1 more source
Direct measurement of free glucocorticoids in small volumes of mouse and rat serum using ultrafiltration and liquid chromatography-tandem mass spectrometry. [PDF]
Mazurenko A, Salehzadeh M, Soma KK.
europepmc +1 more source
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley +1 more source
A rare culprit: Acute pancreatitis associated with anisakiasis. [PDF]
Harada F, Takita M, Saito H, Kami M.
europepmc +1 more source
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen +10 more
wiley +1 more source
The Single‐Nanostructured Optoelectronic Vehicle for neuromodulation Activation (SNOVA) establishes a paradigm for non‐genetic, implant‐free neuromodulation. By integrating NIR‐excitable UCNPs with broadband‐absorbing perovskite QDs, SNOVA efficiently converts deeply penetrating light into localized electric fields that modulate neuronal ion dynamics ...
Luyue Jiang +19 more
wiley +1 more source
Effects of changing the tension of elastic bands of lower-limb orthosis with a trunk belt on lower-limb muscle activity during walking: Evidence from a pilot study. [PDF]
Konishi S, Soma T.
europepmc +1 more source
NRN1 as a therapeutic target for Alzheimer's disease
Abstract INTRODUCTION Neuritin‐1 (NRN1) was identified as a synaptic protein associated with cognitive resilience to Alzheimer's disease (AD). METHODS Target risk score and cell type expression profiles were generated for NRN1 using methods developed by the Emory‐Sage‐SGC‐JAX Target Enablement to Accelerate Therapy Development for Alzheimer's Disease ...
Derian A. Pugh +6 more
wiley +1 more source
Characterizing Microglia Morphology in the Frontal Cortex of Pair-Bonded and Unpaired Prairie Voles (<i>Microtus ochrogaster</i>). [PDF]
Keefauver T, Gobrogge KL.
europepmc +1 more source
Abstract INTRODUCTION The medial prefrontal cortex (mPFC) is critical for executive function, behavioral inhibition, and memory. Its high vulnerability to dementia, compared to other prefrontal regions, remains unclear. METHODS We analyzed post mortem brain tissue from 118 older subjects, including post‐stroke survivors, Alzheimer's disease; vascular ...
Dan D. Jobson +6 more
wiley +1 more source

