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Reprogramming of Somatic Cells to Pluripotency
2010Reprogramming of somatic cells into pluripotent stem cells has been achieved by introducing four transcription factors, Sox2, Oct3/4, Klf4 and c-Myc, in 2006. These induced pluripotent stem (iPS) cells have raised hopes for a new era of regenerative medicine because they can avoid the ethical problems and innate immune rejection associated with ...
Shinya Yamanaka, Masato Nakagawa
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2014
A number of somatic stem cells have been used in inner ear research. In this chapter, two stem cells, mesenchymal and hematopoietic stem cells, are the focus, because these stem cells have already utilized in clinical settings. Of mesenchymal stem cells, the potential of bone marrow- and adipose tissue-derived stem cells for the treatment of the inner ...
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A number of somatic stem cells have been used in inner ear research. In this chapter, two stem cells, mesenchymal and hematopoietic stem cells, are the focus, because these stem cells have already utilized in clinical settings. Of mesenchymal stem cells, the potential of bone marrow- and adipose tissue-derived stem cells for the treatment of the inner ...
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Construction of Somatic Cell Hybrids
Current Protocols in Human Genetics, 1996AbstractSomatic cell hybridization is the method of choice to separate a chromosome of interest from the full chromosome complement and obtain a permanent source of the chromosome. This unit begins with the choice of fusion techniques and selectable markers for hybrids containing a chromosome of interest.
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1986
By somatic cell cytogenetics is meant the study of differentiated cells outside the germline. Since such cells usually do not divide, it is not surprising that much less is known about them than about germline or meristematic cells.
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By somatic cell cytogenetics is meant the study of differentiated cells outside the germline. Since such cells usually do not divide, it is not surprising that much less is known about them than about germline or meristematic cells.
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A tribute to somatic cell reprogrammers
MHR: Basic science of reproductive medicine, 2012For many biologists, the ‘holy grail’ has been to derive pluripotent cells that have the potential to differentiate into all cell types of the body. They represent enormous scientific value as they can be used to study differentiation, the onset of disease and, in the long term, offer a significant therapeutic potential (Colman and Dreesen, 2009). Long
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1973
Publisher Summary This chapter describes the preparation of primary cultures of somatic plant cells. Primary cultures of somatic plant cells have been established from virtually every organ or tissue and from diverse plants, from the moss to the monocotyledonous angiosperm.
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Publisher Summary This chapter describes the preparation of primary cultures of somatic plant cells. Primary cultures of somatic plant cells have been established from virtually every organ or tissue and from diverse plants, from the moss to the monocotyledonous angiosperm.
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1992
Somatic hybridization is a technique which allows the manipulation of cellular genomes by protoplast fusion. Its major contribution to plant breeding is in overcoming common crossing barriers among plant species and in organelle genetics and breeding. Several reviews on different aspects of somatic hybridization were published recently: Pelletier and ...
K. C. Sink, R. K. Jain, J. B. Chowdhury
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Somatic hybridization is a technique which allows the manipulation of cellular genomes by protoplast fusion. Its major contribution to plant breeding is in overcoming common crossing barriers among plant species and in organelle genetics and breeding. Several reviews on different aspects of somatic hybridization were published recently: Pelletier and ...
K. C. Sink, R. K. Jain, J. B. Chowdhury
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Transformationlike Phenomena in Somatic Cells
1968Publisher Summary This chapter explains how to reproduce transformation phenomena by the action of exogenous DNA on somatic cells have been confronted with a number of difficulties, some of which are hardly foreseen. The additional complications arose in connection with the appearance of transformationlike phenomena in experiments with RNA as the ...
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MALIGNANCY AND THE GENETICS OF THE SOMATIC CELL
Annals of the New York Academy of Sciences, 1958openaire +3 more sources