Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation. [PDF]
, 2017 Human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced PSCs (iPSCs), represent potentially unlimited cell sources for clinical applications. Previous studies have suggested that hPSCs may benefit from immune privilege and
Allard, Patrick +12 more
core +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
The epidemiology of mastitis in Australian dairy cattle : a dissertation submitted in partial fulfilment of the requirements for the degree of Masters of Veterinary Studies (Epidemiology) [PDF]
, 2000 This study represents an aggregation of knowledge on mastitis within the Australian dairy industry. Aspects of the epidemiology and economics of mastitis have been collated and areas of missing knowledge identified.
Shephard, Richard William
core
Nature, 1976 Variation, Senescence and Neoplasia in Cultured Somatic Cells. (A Commonwealth Fund Book.) By John W. Little-field. Pp. xi+163. (Harvard University: Cambridge, Massachusetts and London, 1976.) £6.15.
openaire +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Transcriptionally inactive oocyte-type 5S RNA genes of Xenopus laevis are complexed with TFIIIA in vitro [PDF]
, 1987 An extract from whole oocytes of Xenopus laevis was shown to transcribe somatic-type 5S RNA genes approximately 100-fold more efficiently than oocyte-type 5S RNA genes.
Eversole-Cire, Pamela +4 more
core +1 more source
The Genetics of Somatic Mammalian Cells, [PDF]
, 1957 New quantitative techniques have been described for rapid plating of isolated single cells from a wide variety of human tissues under conditions such that almost every cell produces a macroscopic colony. These methods make possible new kinds of studies of the growth and genetics of mammalian cells.
openaire +3 more sources
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Fluorescence microscopy methods for the determination of somatic cell count in raw cow's milk
Veterinární Medicína, 2016 The direct fluorescence microscopy method with ethidium bromide staining can be used for somatic cell counting in raw cow's milk. However, this method has some limitations that may influence the results of the analysis.
P. Zajac +3 more
doaj +1 more source