Results 51 to 60 of about 10,841,366 (345)
Journal of Translational Medicine, 2023 Background The testis is a complex organ that undergoes extensive developmental changes from the embryonic stage to adulthood. The development of germ cells, which give rise to spermatozoa, is tightly regulated by the surrounding somatic cells.
Najmeh Salehi, Mehdi Totonchi
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A Comparative View on Human Somatic Cell Sources for iPSC Generation
Stem Cells International, 2014 The breakthrough of reprogramming human somatic cells was achieved in 2006 by the work of Yamanaka and Takahashi. From this point, fibroblasts are the most commonly used primary somatic cell type for the generation of induced pluripotent stem cells ...
S. Raab +3 more
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The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
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Scientific Reports, 2022 Propagation by somatic embryogenesis in Theobroma cacao has some issues to be solved, as many morphologically abnormal somatic embryos that do not germinate into plants are frequently observed, thus hampering plant production on a commercial scale.
Claudia Garcia +9 more
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FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
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Czech Journal of Animal Science, 2011 The objective of this study was to estimate heritabilities and genetic correlations of lactational and daily somatic cell scores with descriptive and linear type traits in Polish Holstein-Friesian cows.
E. Ptak +3 more
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Germ–Somatic Cell Interactions Are Involved in Establishing the Follicle Reserve in Mammals
Frontiers in Cell and Developmental Biology, 2021 Mammalian females are born with a finite reserve of ovarian follicles, the functional units of the ovary. Building an ovarian follicle involves a complex interaction between multiple cell types, of which the oocyte germ cell and the somatic granulosa ...
Patrícia Rodrigues +7 more
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Reprogramming of Somatic Cell Identity [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2008 All mammalian somatic cells originate from a single fertilized cell, the zygote, and share identical genetic information despite the dramatic changes in cell structure and function that accompany organismal development. The genome is subjected to a wide array of epigenetic modifications during lineage specification, a process that contributes to the ...
Bryce W. Carey +2 more
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Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
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Frontiers in Cell and Developmental BiologyIntroduction: Mesenchymal stromal cells (MSCs) are activated upon inflammation and/or tissue damage and migrate to suppress inflammation and repair tissues.
Akiko Hori +15 more
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