Results 111 to 120 of about 674,037 (393)

On the evolution of differentiated multicellularity [PDF]

arXiv, 2008
Most conspicuous organisms are multicellular and most multicellular organisms develop somatic cells to perform specific, non-reproductive tasks. The ubiquity of this division of labor suggests that it is highly advantageous. In this paper, I present a model to study the evolution of specialized cells.
arxiv  

Does telomere elongation lead to a longer lifespan if cancer is considered? [PDF]

, 2005
As cell proliferation is limited due to the loss of telomere repeats in DNA of normal somatic cells during division, telomere attrition can possibly play an important role in determining the maximum life span of organisms as well as contribute to the process of biological ageing. With computer simulations of cell culture development in organisms, which
arxiv   +1 more source

A flexible model-based framework for robust estimation of mutational signatures [PDF]

arXiv, 2022
Somatic mutations in cancer can be viewed as a mixture distribution of several mutational signatures, which can be inferred using non-negative matrix factorization (NMF). Mutational signatures have previously been parametrized using either simple mono-nucleotide interaction models or general tri-nucleotide interaction models. We describe a flexible and
arxiv  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Effect of Somatic Cell Count on Prato Cheese Composition [PDF]

Journal of Dairy Science, 2007
The objective of this research was to evaluate the effect of 2 levels of somatic cell counts (SCC) in raw milk on Prato cheese composition, protein and fat recovery, cheese yield, and ripening. A 2 x 6 factorial design with 3 replications was performed in this study: 2 levels of SCC and 6 levels of storage time.
G. Mazal, Marcos Veiga dos Santos, P. C. B. Vianna, Mirna Lúcia Gigante   +3 more
openaire   +3 more sources

Change in composition and quality of milk as a function of volume of production, year period and milking systems and cooling

Semina: Ciências Agrárias, 2015
Aimed to evaluate the effect of three volumes monthly milk sales, months of year, types of coolers and milking systems on the freezing point of milk, fat percentage, somatic cell count (SCC) and bacterial count Total (CBT) milk come from producers that ...
Loreno Egidio Taffarel , Patricia Barcellos Costa , Claudio Yuji Tsutsumi , Elcio Silvério Klosowski , Eduardo Fonseca Portugal , Antonio Carlos Lins   +5 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Using the somatic cell count report

Kansas Agricultural Experiment Station Research Reports, 1996
Mammary gland health and milk quality have a direct effect on a dairy's profit. In fact, these are the most costly health problems on dairy farms. Yet, many producers are unaware of losses from mammary health because subclinical mastitis, which is not visually observed, is the most common problem.
openaire   +3 more sources

Somatic cell counts in dairy marketing: quantile regression for count data

European Review of Agricultural Economics, 2015
We study the determinants of somatic cell count (SCC) for farm milk among US dairies. We synthesise much of the work that has been done to model SCC determinants in order to identify the potential impacts of buyer-imposed penalties and incentives within the supply chain.
Volpe, Richard, Park, Timothy, Dong, Fengxia, Jensen, Helen   +3 more
openaire   +5 more sources

Combining mutation and recombination statistics to infer clonal families in antibody repertoires [PDF]

arXiv, 2022
B-cell repertoires are characterized by a diverse set of receptors of distinct specificities generated through two processes of somatic diversification: V(D)J recombination and somatic hypermutations. B cell clonal families stem from the same V(D)J recombination event, but differ in their hypermutations.
arxiv