Results 181 to 190 of about 42,166 (286)

Derivation of embryonic stem cells from cloned blastocysts using improved somatic cell nuclear transfer in common marmosets. [PDF]

Stem Cell Reports
Matoba S, Kurotaki Y, Funaya S, Yamada Y, Ogonuki N, Shinohara H, Yamamoto M, Yoneda N, Homma T, Higuchi Y, Sasaki E, Ogura A.   +11 more
europepmc   +1 more source

Combined Chaetocin/Trichostatin A Treatment Improves the Epigenetic Modification and Developmental Competence of Porcine Somatic Cell Nuclear Transfer Embryos. [PDF]

Front Cell Dev Biol, 2021
Jeong PS, Yang HJ, Park SH, Gwon MA, Joo YE, Kim MJ, Kang HG, Lee S, Park YH, Song BS, Kim SU, Koo DB, Sim BW.   +12 more
europepmc   +1 more source

Changing cell fate by nuclear reprogramming

, 2005
The differentiated state of somatic cells is remarkably stable, but nuclear transfer can efficiently override the stability of cell differentiation by nuclear reprogramming.
Gurdon, J. B., Simonsson, Stina,
core  

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Lycopene enhances epigenetic reprogramming and zygotic genome activation in the porcine somatic cell nuclear transfer embryo. [PDF]

Sci Rep
Yun JH, Kang HG, Choi EY, Jeon SB, Kim MJ, Jeong PS, Song BS, Kim SU, Min KS, Sim BW.   +9 more
europepmc   +1 more source

Correction: Defective chromatin architectures in embryonic stem cells derived from somatic cell nuclear transfer impair their differentiation potentials. [PDF]

Cell Death Dis, 2021
Wu DY, Li X, Sun QR, Dou CL, Xu T, He H, Luo H, Fu H, Bu GW, Luo B, Zhang X, Ma BG, Peng C, Miao YL.   +13 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

H3K9me3 and H3K27me3 are epigenetic barriers to somatic cell nuclear transfer in rabbits. [PDF]

Am J Transl Res
Gao Y, Wu F, Tang D, Chen X, Chen Q, Chen Y, Fang K, Chen W, Du F, Liu Z.   +9 more
europepmc   +1 more source

Comparative evaluation of three different formulas for predicting the parturition date of German Shepherds following somatic cell nuclear transfer. [PDF]

J Vet Med Sci, 2021
Son YB, Jeong YI, Hossein MS, Olsson PO, Kim G, Jeong YW, Hwang WS.   +6 more
europepmc   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source