Results 51 to 60 of about 830,877 (285)

Tinnitus, hyperacusis and somatic complaints in a diverse Norwegian clinical population: implications for assessment and rehabilitation

Annals of Medicine
Objectives Patients with tinnitus often have somatic complaints, a reality that is understudied in the broader literature on tinnitus. This study aims to characterize tinnitus patients with somatic complaints, investigate associations between somatic ...
Tove Bring Solum, Andreas Falck, Kaia Ringstad Andreassen, Guri Engernes Nielsen   +3 more
doaj   +1 more source

The role of leptin in indirectly mediating “somatic anxiety” symptoms in major depressive disorder

Frontiers in Psychiatry, 2022
BackgroundLeptin is a multifunctional hormone secreted from adipose tissue, which plays a core role in regulating energy intake and expenditure. Evidence has demonstrated that leptin receptors are located in brain areas involved in emotional processing ...
Yue Zhu, Yue Zhu, Yange Wei, Yange Wei, Jia Duan, Jia Duan, Jianing Li, Ran Zhang, Ran Zhang, Jiaze Sun, Jiaze Sun, Pengshuo Wang, Pengshuo Wang, Zhuang Liu, Jing Lv, Jing Lv, Jing Lv, Shengnan Wei, Shengnan Wei, Xiaowei Jiang, Xiaowei Jiang, Fei Wang, Fei Wang, Fei Wang, Yanqing Tang, Yanqing Tang, Yanqing Tang   +26 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Correlation of somatic dysfunction with gastrointestinal endoscopic findings: An observational study

, 2016
Context: Gastrointestinal (GI) endoscopy provides a novel means of correlating visceral abnormalities with somatic dysfunction. Objective: To assess the correlation of palpatory findings of somatic dysfunction with GI abnormalities determined by ...
Snider, Eric J., Johnson, Jane C., Ngo, Christopher S., Schneider, Robert P., Lehnardt, Charles W., Sheneman, Timothy A., Snider, Karen T., Danto, Jay B.   +7 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Epigenetic reprogramming of somatic cells by zygotic factors [PDF]

, 2009
Cloning cattle using somatic cell nuclear transfer (SCNT) is an inefficient process, with approximately only 5% of transferred embryos developing to live offspring.
Sowry, Blair Gavin
core  

Impact of job burnout on mental health among social workers in public and private sector in Greece

Mental Health, 2019
Purpose: This study examines the impact of job burnout on the social workers’ mental health in public and private sector. Material and Method: A descriptive, cross-sectional study was conducted in which 103 social workers who were working in public (n=
Konstantinos Tsaras, Dr., Maria Malliarou, Dr, Stiliani Kotrotsiou, Dr., Ioanna V. Papathanasiou, Dr., Evangelia Christopoulou, Dr., Evangelos C. Fradelos, Dr.   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source