Results 71 to 80 of about 830,877 (285)

Sexual dysfunction: conceptual and measurement issues [PDF]

Despite a standard classification and array of self-report questionnaires, there is little consensus about how to define and measure sexual dysfunction.
Mitchell, Kirstin Rebecca
core   +1 more source

ATM-dependent DNA damage response constrains cell growth and drives clonal hematopoiesis in telomere biology disorders

The Journal of Clinical Investigation
Telomere biology disorders (TBDs) are genetic diseases caused by defective telomere maintenance. TBD patients often develop bone marrow failure and have an increased risk of myeloid neoplasms.
Christopher M. Sande, Stone Chen, Dana V. Mitchell, Ping Lin, Diana M. Abraham, Jessie Minxuan Cheng, Talia Gebhard, Rujul J. Deolikar, Colby Freeman, Mary Zhou, Sushant Kumar, Michael Bowman, Robert L. Bowman, Shannon Zheng, Bolormaa Munkhbileg, Qijun Chen, Natasha L. Stanley, Kathy Guo, Ajibike Lapite, Ryan Hausler, Deanne M. Taylor, James Corines, Jennifer J.D. Morrissette, David B. Lieberman, Guang Yang, Olga Shestova, Saar Gill, Jiayin Zheng, Kelcy Smith-Simmer, Lauren G. Banaszak, Kyle N. Shoger, Erica F. Reinig, Madilynn Peterson, Peter Nicholas, Amanda J. Walne, Inderjeet Dokal, Justin P. Rosenheck, Karolyn A. Oetjen, Daniel C. Link, Andrew E. Gelman, Christopher R. Reilly, Ritika Dutta, R. Coleman Lindsley, Karyn J. Brundige, Suneet Agarwal, Alison A. Bertuch, Jane E. Churpek, Laneshia K. Tague, F. Brad Johnson, Timothy S. Olson, Daria V. Babushok   +50 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Physical illness in schizophrenia and the role of tolerability in antipsychotic selection: an expert consensus with a focus on cariprazine

Annals of General Psychiatry
Background Schizophrenia is a highly heterogeneous disease, and a high percentage of patients are at high risk of developing somatic comorbidities, which must be taken into account in disease management and treatment selection.
Alessandro Cuomo, Giovanni B. Forleo, Taieb Ghodhbane, Jon Johnsen, Angel L. Montejo, Cristina Vilares Oliveira, Toby Pillinger, Jose Antonio Ramos-Quiroga, Myrto Samara, Paul H. B. Seerden, Thomas Thomas Stoeckl, Andrea Fagiolini   +11 more
doaj   +1 more source

Somatic dysfunction increase during caffeine withdrawal

Journal of Osteopathic Medicine, 1997
Abstract The authors studied the effects of caffeine withdrawal on 14 subjects at baseline and during a 4-day period of abstinence from caffeine. They studied the results from quantitative electroencephalograms performed on these subjects and gauged any changes that may have been evoked during this withdrawal period.
R R, Reeves, F A, Struve, G, Patrick
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Female Sexual Function During the Menopausal Transition in a Group of Iranian Women

Journal of Family and Reproductive Health, 2016
Objective: To determine the prevalence of sexual problems in Iranian women and association of sexual dysfunction with menopausal symptoms. Materials and methods: In this cross-sectional study, 151 married women with the age of 40-60 yearsold who were ...
Tahereh Eftekhar, Mahboobeh Dashti, Mamak Shariat, Fedyeh Haghollahi, Firoozeh Raisi, Akram Ghahghaei-Nezamabadi   +5 more
doaj  

Can MMPI-2-RF confirm the structural validity of the somatoform spectrum of the Hierarchical Taxonomy of Psychopathology (HiTOP) in patients with chronic low back pain

Acta Psychologica
Objectives: This study aimed to evaluate the structural validity of the somatoform spectrum within the context of the Hierarchical Taxonomy of Psychopathology (HiTOP) model in patients with chronic low back pain.
Shahin Sadeghi, Abbas Pourshahbaz, Shima Shakiba, Seyed Majid Akhavan Hejazi, Mohamadreza Davoudi   +4 more
doaj   +1 more source

Relationship between gynecological disorders and related pathological conditions in immature girl harmed due to military actions and armed conflicts

Zdorovʹe Rebenka, 2018
Background. Nowadays, the problem of a comprehensive approach to detecting and treatment of each patient has been again brought up to date. Modern medicine is characterized by a large number of new diagnostic techniques and a huge variety of therapeutic ...
V.O. Dynnik
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source