Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Efficacy of manual therapy on somatic tinnitus dual modulatory factors: a study protocol
BACKGROUND AND PURPOSE: The literature has shown promising effect of manual therapy in improving the severity of somatic tinnitus.However, no previous study has concentrated onevaluating the combined effect of temporomandibular joint and cervical spine
Palak Sharma +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Basic Psychological Need Satisfaction, Stress-Related Appraisals, and Dancers’ Cortisol and Anxiety Responses \ud [PDF]
Self-determination theory (Deci & Ryan, 2000) posits basic psychological need satisfaction (BPNS) as essential for optimal functioning and health. Grounded in this framework, the current study examined the role of BPNS in dancers’ cognitive appraisals ...
Bosch, J. +5 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Motor Coordination as a Creation Device: a somatic approach in contemporary dance
This article postulates that Somatic Education integrates similar issues related to perception in both cognitive science and philosophy. It also indicates that somatic approaches can expand their area of action, overcoming their original role in health ...
Paloma Bianchi +1 more
doaj +2 more sources
Sensory-Motor Amnesia and Somatic Solutions [PDF]
PURPOSE The purpose of this study was to identify the neurophysiological mechanisms of Sensory-Motor Amnesia (SMA) and to understand the clinical basis of Hanna's somatic education as a somatic solution.
Jeong Myung Gim
doaj +1 more source
East African HIV care: depression and HIV outcomes. [PDF]
Importance:Depression is a common co-morbidity for people living with HIV (PLWH) and is associated with elevated plasma HIV RNA levels. While depression correlates with deficits in antiretroviral (ARV) adherence, little data exist to inform the ...
Adamu, Y +10 more
core
Psychological well-being in parents of pediatric patients with TD1. Role of Family Conflict and Parental Fear of Children\u2019s Self-injecting on Their Glycaemic Control and Psychological Well-being [PDF]
Aims: This study aims to assess psychological well-being and life perceptions in parents of paediatric patients with T1D and to identify how the parents\u2019 fear of children\u2019s self-injecting and conflicts could influence the paediatric patients ...
Bonichini, Sabrina +4 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

