Results 61 to 70 of about 260,984 (298)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

EMOTIONAL TRANSFORMATION THROUGH THE EFFECTS OF SOMATIC THERAPY TECHNIQUES IN REDUCING DEPRESSION AMONG STUDENTS OF SKILL TRAINING INSTITUTIONS

The International Journal of Humanities Technology and Civilization
Depression among students of higher education institutions is an increasingly worrying issue, with negative effects on mental well-being and academic performance.
Norizan Yusof
doaj   +1 more source

The Use of Complementary and Alternative Medicine for Menopausal Symptoms among Chinese-American Women [PDF]

, 2009
The objectives of this research were to study the use of complementary and alternative medicine (CAM) for menopausal symptoms among Chinese-American women, and to examine the correlation between CAM use, acculturation, and CAM insurance coverage.
Chung, Rebecca Kwai-Ying
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Development of Somatic Complaints Among Adolescents and Young Adults in Switzerland

Swiss Journal of Sociology, 2018
In this study we explored the development of somatic complaints among adolescents and young adults aged 16 to 30 years in Switzerland. Using data from the Transitions from Education to Employment (TREE) study, we applied a hidden Markovian model with ...
Berchtold André, Surís Joan-Carles, Meyer Thomas, Taushanov Zhivko   +3 more
doaj   +1 more source

Differences in reporting somatic complaints in elderly by education level [PDF]

Open Medicine, 2012
Abstract
Stankunas, Mindaugas, Soares, Joaquim FJ, Stankuniene, Aurima, Melchiorre, M Gabriella, Torres-Gonzales, Francisco, Ioannidi-Kapolou, Elisabeth, Barros, Henrique, Lindert, Jutta   +7 more
openaire   +5 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Somatisation in primary care: A comparative study of Australians, Latin Americans, Vietnamese, and Polish living in Australia [PDF]

, 2018
This study identified differences in somatisation symptoms, psychiatric status, and the relationship between acculturation and somatisation. It also investigated GP’s (general practitioners) ability to detect somatisation in primary healthcare setting. A
Gonzales, Hugo M
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source