Results 41 to 50 of about 334,411 (359)

Somatic mutations in human ageing: New insights from DNA sequencing and inherited mutations [PDF]

open access: yesarXiv, 2023
The accumulation of somatic mutations is a driver of cancer and has long been associated with ageing. Due to limitations in quantifying mutation burden with age in non-cancerous tissues, the impact of somatic mutations in other ageing phenotypes is unclear.
arxiv  

Brownian-like deviation of neighboring cells in the early embryogenesis of the zebrafish [PDF]

open access: yesPhysical Biology, Institute of Physics: Hybrid Open Access, 2019, 16 (2), pp.024001, 2019
We investigate cell trajectories during zebrafish early embryogenesis based on 3D+time photonic microscopy imaging data. To remove the collective flow motion and focus on fluctuations, we analyze the deviations of pairs of neighboring cells. These deviations resemble Brownian motion and reveal different behaviors between pairs containing daughter cells
arxiv   +1 more source

Functional characterization of a novel TP53RK mutation identified in a family with Galloway–Mowat syndrome

open access: yesHuman Mutation, Volume 43, Issue 12, Page 1866-1871, December 2022., 2022
Abstract Galloway–Mowat syndrome (GAMOS) is a very rare condition characterized by early‐onset nephrotic syndrome and microcephaly with variable neurologic features. While considerable genetic heterogeneity of GAMOS has been identified, the majority of cases are caused by pathogenic variants in genes encoding the four components of the Kinase ...
Ernestine Treimer   +8 more
wiley   +1 more source

Long-Term Maintainable Somatic Embryogenesis System in Alfalfa (Medicago sativa) Using Leaf Explants: Embryogenic Sustainability Approach

open access: yesPlants, 2019
Alfalfa (Medicago sativa) is one of the most important forage legume crops because of its mass production and high feeding value. It originated in Asia and is one of the most ancient plants cultivated throughout the world as a fodder.
Ankush Sangra   +2 more
doaj   +1 more source

Thyroid‐like hormone signaling in invertebrates and its potential role in initial screening of thyroid hormone system disrupting chemicals

open access: yesIntegrated Environmental Assessment and Management, Volume 19, Issue 1, Page 63-82, January 2023., 2023
Abstract This review examines the presence and evolution of thyroid‐like systems in selected aquatic invertebrates to determine the potential use of these organisms in screens for vertebrate thyroid hormone axis disrupting chemicals (THADCs). Such a screen might support the phasing out of some vertebrate testing.
Jane E. Morthorst   +4 more
wiley   +1 more source

Imaging Parhyale hawaiensis embryogenesis with frequency domain photoacoustic microscopy: A novel tool in developmental biology

open access: yesJournal of Biophotonics, Volume 15, Issue 12, December 2022., 2022
We introduce a novel, low‐cost photoacoustic microscope, which is capable of listening to the laser light interactions with developing embryos of Parhyale hawaiensis emerging model organism. The presented label‐free imaging approach delineates the morphological features of the specimens with high resolution and contrast specificity, shedding light on ...
George J. Tserevelakis   +5 more
wiley   +1 more source

Somatic Embryogenesis: Identified Factors that Lead to Embryogenic Repression. A Case of Species of the Same Genus.

open access: yesPLoS ONE, 2015
Somatic embryogenesis is a powerful biotechnological tool for the mass production of economically important cultivars. Due to the cellular totipotency of plants, somatic cells under appropriate conditions are able to develop a complete functional embryo.
Geovanny I Nic-Can   +5 more
doaj   +1 more source

Oil Palm Phytochrome-Interacting Factor4 (PIF4) Gene is Conserved and Highly Expressed During Somatic Embryogenesis

open access: yesHayati Journal of Biosciences, 2019
Oil palm is used in food, fuel and cosmetic industries. Tissue culture is the best way to propagate oil palm; unfortunately the somatic embryogenesis during tissue culture takes long time.
Mantira Suksirt   +4 more
doaj   +1 more source

Abnormalities in somatic embryogenesis caused by 2,4-D: an overview

open access: yesPlant Cell Tissue and Organ Culture, 2019
Somatic embryogenesis is a morphogenetic event where somatic cells have the ability to produce embryos without gamete fusion. It is used as a technique for plant mass propagation.
Claudia Garcia   +6 more
semanticscholar   +1 more source

Multi‐omics analyses reveal epigenomics basis for cotton somatic embryogenesis through successive regeneration acclimation process

open access: yesPlant Biotechnology Journal, 2018
Summary Plant regeneration via somatic embryogenesis is time‐consuming and highly genotype‐dependent. The plant somatic embryogenesis process provokes many epigenetics changes including DNA methylation and histone modification.
Jianying Li   +7 more
semanticscholar   +1 more source

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