Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Maturation and germination of somatic embryos of Sorghum bicolor (L.) Moench cultivar 'CIAP 132R-05'
Biotecnología Vegetal, 2017 In sorghum [Sorghum bicolor (L.) Moench], developed protocols for plant regeneration via somatic embryogenesis do not include maturation stage. The present work was carried out with the aim of achieving the maturation and germination of sorghum somatic ...
Silvio de J Martínez +6 more
doaj
Efficient Transformation of Somatic Embryos and Regeneration of Cork Oak Plantlets with A Gene (CsTL1) Encoding a Chestnut Thaumatin-Like Protein. [PDF]
Int J Mol Sci, 2021 Cano V +5 more
europepmc +1 more source
Advanced Science, EarlyView.We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang +10 more
wiley +1 more source
Advanced Science, EarlyView.Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat +6 more
wiley +1 more source
Somatic embryogenesis in Carica papaya L. var. Maradol rojo
Biotecnología Vegetal, 2007 The most important papaya variety in Cuba is Red Maradol. However, it is susceptible to the main viral diseases that attack this crop. For this reason, it is necessary to establish a method for plant regeneration via somatic embryogenesis as the base to ...
Laisyn Posada-Pérez +2 more
doaj
Shotgun label-free proteomic and biochemical study of somatic embryos (cotyledonary and maturation stage) in Catharanthus roseus (L.) G. Don. [PDF]
3 Biotech, 2021 Gulzar B +7 more
europepmc +1 more source
Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1
Advanced Science, EarlyView.Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency +19 more
wiley +1 more source
Induction of Hairy Roots on Somatic Embryos of Rhizoclones from Typha domingensis Seedlings. [PDF]
Plants (Basel), 2020 Hernández-Piedra G +4 more
europepmc +1 more source
Proteome-Wide Analysis of Heat-Stress in Pinus radiata Somatic Embryos Reveals a Combined Response of Sugar Metabolism and Translational Regulation Mechanisms. [PDF]
Front Plant Sci, 2021 Castander-Olarieta A +8 more
europepmc +1 more source