Results 151 to 160 of about 18,035 (205)

Correction: Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY. [PDF]

open access: yesLeukemia, 2023
Mansouri L   +61 more
europepmc   +1 more source

A Novel AICDA Splice-Site Mutation in Two Siblings with HIGM2 Permits Somatic Hypermutation but Abrogates Mutational Targeting. [PDF]

open access: yesJ Clin Immunol, 2022
Dirks J   +8 more
europepmc   +1 more source

The role of HIRA-dependent H3.3 deposition and its modifications in the somatic hypermutation of immunoglobulin variable regions. [PDF]

open access: yesProc Natl Acad Sci U S A, 2021
Yu G   +6 more
europepmc   +1 more source

Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape

open access: yes, 2022
Schoeberl UE   +14 more
europepmc   +1 more source

A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome. [PDF]

open access: yesJ Clin Immunol
Della Mina E   +16 more
europepmc   +1 more source

Towards an understanding of somatic hypermutation

Current Opinion in Immunology, 2001
How germinal center (GC) B cells diversify their rearranged immunoglobulin genes by somatic hypermutation is unknown. However, the GC-specific activation-induced cytidine deaminase has been identified as a key factor controlling two central GC-specific events: somatic hypermutation and class-switch recombination of immunoglobulin genes. This factor may
Heinz Jacobs
exaly   +3 more sources

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