Results 161 to 170 of about 20,554 (213)

A Novel AICDA Splice-Site Mutation in Two Siblings with HIGM2 Permits Somatic Hypermutation but Abrogates Mutational Targeting. [PDF]

J Clin Immunol, 2022
Dirks J, Haase G, Cantaert T, Frey L, Klaas M, Rickert CH, Girschick H, Meffre E, Morbach H.   +8 more
europepmc   +1 more source

[High-throughput sequencing in identifying somatic hypermutation in immunoglobulin heavy chain variable regions with complex clonal backgrounds]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Gao MG, Wei R, Liu Y, Huang XJ, Yang SM, Zhao XS.   +5 more
europepmc   +1 more source

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches. [PDF]

J Vis Exp, 2021
Sible E, Zheng S, Choi JE, Vuong BQ.
europepmc   +1 more source

What Targets Somatic Hypermutation to the Immunoglobulin Loci? [PDF]

Viral Immunol, 2020
Heltzel JMH, Gearhart PJ.
europepmc   +1 more source

Correction: Single-cell transcriptome profiling and the use of AID deficient mice reveal that B cell activation combined with antibody class switch recombination and somatic hypermutation do not benefit the control of experimental trypanosomosis. [PDF]

PLoS Pathog
Nguyen HTT, Guevarra RB, Magez S, Radwanska M.   +3 more
europepmc   +1 more source

Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape

, 2022
Schoeberl UE, Fitz J, Froussios K, Valieris R, Ourailidis I, Makharova M, Bauer B, Neumann T, Wiedemann E, Steininger M, Garcia AC, Mastrovito M, Mouquet H, Da Silva IT, Pavri R.   +14 more
europepmc   +1 more source

Proteomic analysis of the Rad18 interaction network in DT40 [PDF]

, 2009
Sreekumar, Sushmita Gowri
core  

A Novel Heterozygous Variant in AICDA Impairs Ig Class Switching and Somatic Hypermutation in Human B Cells and is Associated with Autosomal Dominant HIGM2 Syndrome. [PDF]

J Clin Immunol
Della Mina E, Jackson KJL, Crawford AJI, Faulks ML, Pathmanandavel K, Acquarola N, O'Sullivan M, Kerre T, Naesens L, Claes K, Goodnow CC, Haerynck F, Kracker S, Meyts I, D'Orsogna LJ, Ma CS, Tangye SG.   +16 more
europepmc   +1 more source

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Towards an understanding of somatic hypermutation

Current Opinion in Immunology, 2001
How germinal center (GC) B cells diversify their rearranged immunoglobulin genes by somatic hypermutation is unknown. However, the GC-specific activation-induced cytidine deaminase has been identified as a key factor controlling two central GC-specific events: somatic hypermutation and class-switch recombination of immunoglobulin genes. This factor may
Heinz Jacobs
exaly   +3 more sources