Results 191 to 200 of about 200,238 (297)

The somatic mutation landscape of normal gastric epithelium. [PDF]

Nature
Coorens THH, Collord G, Jung H, Wang Y, Moore L, Hooks Y, Mahbubani K, Law SYK, Yan HHN, Yuen ST, Saeb-Parsy K, Campbell PJ, Martincorena I, Leung SY, Stratton MR.   +14 more
europepmc   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

Bile cell-free DNA shows benefit as a potential sample for somatic mutation detection of resectable cholangiocarcinoma. [PDF]

ILIVER
Liu S, Ma X, Zhuang H, Wang B, Wang Q, Hua Y, Zhang Z, Xiao Y, Wan J, Chen Y, Shang C.   +10 more
europepmc   +1 more source

A Versatile Microfluidic Extrusion‐Based Hydrogel Platform for Self‐Organization and Long‐Term Maintenance of Engineered 3D Lymphatic Endothelium

Advanced Healthcare Materials, EarlyView.
Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi, Adeline Boyreau, Laura Chaillot, Wilfried Souleyreau, Laetitia Andrique, Pierre‐Olivier Guichet, Thomas Mathivet, Andreas Bikfalvi, Pierre Nassoy   +8 more
wiley   +1 more source

Somatic mutation as an explanation for epigenetic aging. [PDF]

Nat Aging
Koch Z, Li A, Evans DS, Cummings S, Ideker T.   +4 more
europepmc   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

Common origin and somatic mutation patterns of composite lymphomas and leukemias. [PDF]

Leukemia
Berg V, Lollies A, Schneider M, Johansson P, Weniger MA, Albertini E, Facchetti F, Ascani S, Moawia A, Bens S, Fischer A, Siebert R, Klapper W, Lorenzi L, Tiacci E, Hartmann S, Budeus B, Hansmann ML, Küppers R.   +18 more
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

A challenging case of giant atypical fibroxanthoma on non-chronically sun-damaged skin: a case report with TP53 somatic mutation (c.375+1 G>A). [PDF]

Nagoya J Med Sci
Zorlu Ö, Karabağ S, Aşıkovalı S.
europepmc   +1 more source