Results 191 to 200 of about 113,927 (297)

Impact of endogenous sonosensation on <i>in vivo</i> sonogenetics. [PDF]

open access: yesiScience
Xian Q   +11 more
europepmc   +1 more source

Brain Imaging Changes Following Deep Brain Stimulation Patients with Parkinson's Disease: A Literature Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's Disease (PD) is a progressive neurodegenerative disorder primarily characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Structural brain changes, including atrophy in the midbrain, basal ganglia, and cortical regions such as the frontal and temporal lobes, are observed in advanced stages.
Suraiya Mangra   +5 more
wiley   +1 more source

The Second Hit Hypothesis in Animal and Human Dystonia: The Role of Peripheral Nerve Trauma and Spinal Cord Injury

open access: yesMovement Disorders, EarlyView.
The “second‐hit” hypothesis proposes that both a genetic predisposition and an environmental insult—such as peripheral nerve trauma or spinal cord injury—are required for dystonia development. This review explores how neuroinflammation and maladaptive plasticity, triggered by nerve and spinal cord injury, contribute to dystonia pathogenesis.
Lisa Harder‐Rauschenberger   +1 more
wiley   +1 more source

A Network Centered on the Visual‐Motor Cortex Is Critically Involved in Postural Abnormality in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Postural abnormality (PA) is a key motor symptom in Parkinson's disease (PD) that leads to disability and death. However, the pathophysiology underlying PA is still unknown. Objective The objective of this study was to explore the neural patterns behind PAs and measures toward functional restoration using repetitive transcranial ...
Zhuang Wu   +9 more
wiley   +1 more source

Polyelectromyography Under Propofol to Differentiate Functional from Idiopathic Dystonia: A Pilot Study

open access: yesMovement Disorders, EarlyView.
Abstract Background Functional dystonia (FD) is one of the most diagnostically challenging functional movement disorders. Phenomenological features often lack specificity, as many are also observed in idiopathic dystonia (ID) and validated biomarkers to distinguish FD from ID are currently unavailable Objective To investigate potential differences in ...
Roberto Eleopra   +17 more
wiley   +1 more source

Functional Connectivity to the Cerebellum and Resting‐State Networks Predict Earlier Improvement of Dystonia Following Globus Pallidus Internus‐Deep Brain Stimulation (GPi‐DBS)

open access: yesMovement Disorders, EarlyView.
Early improvement of dystonia after globus pallidus internus‐deep brain stimulation (GPi‐DBS) is associated with stimulation of the globus pallidus externus‐subthalamic nucleus (GPe‐STN) fibers and the lenticular fasciculus. Functional connectivity to the cerebellar cortex and the limbic and default mode networks predict early improvement of symptoms ...
A. Enrique Martinez‐Nunez   +9 more
wiley   +1 more source

Longitudinal Awake Mouse fMRI During Voluntary Locomotion Using Zero TE Imaging and a Novel Treadmill Training Protocol

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Functional MRI (fMRI) in awake rodents presents countless valuable opportunities for researchers to probe questions that may not be accessible through anesthetized models, such as voluntary locomotion. The commonly used echo planar imaging (EPI) sequence is highly sensitive to motion that occurs even outside of the imaging plane ...
Lauren Daley   +3 more
wiley   +1 more source

Next Generation 7 Tesla Arterial Spin Labeling With Rotated Spiral Acquisition Enables Mesoscale Resolution in 3D Brain Perfusion and Functional MRI

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To achieve high resolution (≤ 1 mm isotropic) whole‐brain perfusion imaging at 7 T with next generation ASL pulse sequence, reconstruction algorithm, and MRI hardware. Methods We capitalized on three major innovations: (1) FLASH‐based pseudo‐Continuous ASL (pCASL) sequence with rotated golden‐angle stack‐of‐spirals (rGA‐SoS) sampling; (
Chenyang Zhao   +8 more
wiley   +1 more source

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