Results 81 to 90 of about 138,830 (301)

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

open access: yesAdvanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen   +12 more
wiley   +1 more source

The Somatosensory Mismatch Negativity

open access: yesEuropean Journal of Neuroscience
ABSTRACT Mismatch negativity (MMN) is a well‐established neural signature of automatic change detection in the auditory modality. Growing evidence suggests that analogous responses exist in other sensory domains, including somatosensation.
Miro Grundei   +4 more
openaire   +2 more sources

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang   +9 more
wiley   +1 more source

Seeing the body distorts tactile size perception [PDF]

open access: yes, 2013
Vision of the body modulates somatosensation, even when entirely non-informative about stimulation. For example, seeing the body increases tactile spatial acuity, but reduces acute pain.
Longo, Matthew R.   +2 more
core   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

open access: yesAdvanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong   +8 more
wiley   +1 more source

Deficits in Behavioral Functions of Intact Barrel Cortex Following Lesions of Homotopic Contralateral Cortex

open access: yesFrontiers in Systems Neuroscience, 2018
Focal unilateral injuries to the somatosensory whisker barrel cortex have been shown cause long-lasting deficits in the activity and experience-dependent plasticity of neurons in the intact contralateral barrel cortex.
Rahul Chaudhary, V. Rema
doaj   +1 more source

Somatosensory Evoked Potentials In Patients With Juvenile Myoclonic Epilepsy

open access: yes, 2016
WOS: 000390945000002While a small number of studies dealing with somatosensory evoked potential (SEP) have demonstrated hyperexcitability in the primary somatosensory cortex of juve-nile myoclonic epilepsy (JME) patients, the underlying mechanisms have ...
Oge, Ali Emre   +7 more
core   +1 more source

An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli

open access: yesAdvanced Science, EarlyView.
An innervated human skin equivalent is integrated with high‐density microelectrode arrays to reveal how engineered free nerve ending–like structures translate touch and temperature into electrical codes. Mechanical indentation and thermal stimulation engage the engineered somatosensory circuitry and evoke distinct firing and waveform signatures ...
Daniele Bellantoni   +6 more
wiley   +1 more source

Tactile Location Perception Encoded by Gamma-Band Power

open access: yesBioengineering
Background: The perception of tactile-stimulation locations is an important function of the human somatosensory system during body movements and its interactions with the surroundings.
Qi Chen, Yue Dong, Yan Gai
doaj   +1 more source

Cortical pain responses in human infants [PDF]

open access: yes, 2006
Despite the recent increase in our understanding of the development of pain processing, it is still not known whether premature infants are capable of processing pain at a cortical level.
Meek, J   +6 more
core  

Home - About - Disclaimer - Privacy