Results 161 to 170 of about 82,531 (311)

The role of protein arginine methyltransferases in sickle cell‐mediated neurovascular impairments in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Sickle cell disease (SCD) is a hereditary blood disorder caused by mutation of β‐globin. In SCD, haemoglobin polymerization causes red blood cells to assume a rigid sickle‐shape leading to neurovascular alterations, including development of vascular dementia – characterized by cognitive impairment and reduced cerebral perfusion ...
Julia Zaccarelli‐Magalhães   +11 more
wiley   +1 more source

Neurodevelopmental Phenotypes and Brain Anomalies in Individuals With Heterozygous SEMA6A Variants

open access: yesClinical Genetics, EarlyView.
SEMA6A plays a role in cell migration and axon guidance in the developing central nervous system. Phenotypes seen in eleven individuals heterozygous for SEMA6A variants included developmental delay, intellectual disability, autism/autistic behaviors, behavioral abnormalities, attention disorders, hypotonia, and brain anomalies.
Evan Burchfiel   +27 more
wiley   +1 more source

Somatosensory cortex neuronal integrity is altered after stroke. [PDF]

open access: yesFront Hum Neurosci
Cheema R   +4 more
europepmc   +1 more source

Neuroimaging and neurophysiology in infantile‐onset epilepsy after neonatal stroke

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This population‐based retrospective cohort study of 55 newborn infants demonstrated that neonatal MRI and neonatal neurophysiology (amplitude‐integrated EEG, conventional EEG, and somatosensory evoked potentials) combined with follow‐up EEGs during the first year of life provide practical tools for identifying infants at the highest risk of developing ...
Sinikka La Grassa   +6 more
wiley   +1 more source

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

open access: yesThe FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester   +11 more
wiley   +1 more source

Modeling 2D spatio-tactile population receptive fields of the fingertip in human primary somatosensory cortex. [PDF]

open access: yesImaging Neurosci (Camb)
Stoll S   +6 more
europepmc   +2 more sources

What makes a lonely child: environmental, health, and multimodal neuroimaging correlates of prospective loneliness in the ABCD study

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background Loneliness in childhood is a growing public health concern, yet early multilevel candidate risk and protective factors remain insufficiently mapped. Systematic investigation is essential to guide prevention and intervention during sensitive developmental periods.
Ting Yat Wong   +9 more
wiley   +1 more source

Fish welfare in a changing world: New developments and current challenges

open access: yesJournal of Fish Biology, EarlyView.
Abstract The welfare of non‐human animals is central to ethical discussions on animal use, with increasing attention to fish welfare across research, aquaria, aquaculture, and fisheries. This paper reviews current theoretical approaches to animal welfare and recent advances in defining and assessing fish welfare since the seminal paper by Huntingford ...
Sonia Rey Planellas   +16 more
wiley   +1 more source

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