Results 201 to 210 of about 437,838 (300)

Single human fingertip mechanoreceptive afferents simultaneously encode multidimensional aspects of touch

The Journal of Physiology, EarlyView.
Abstract figure legend Mechanoreceptors in the fingertip skin allow us to explore objects and to feel a vast range of textures. We recorded responses from individual low‐threshold mechanoreceptive afferents in humans while dynamic stimuli were swept across their receptive fields, systematically varying force, velocity and spatial period.
Victoria Ashley Lang, Helena Backlund Wasling, Rochelle Ackerley, Johan Wessberg   +3 more
wiley   +1 more source

Probabilistic Perceptual Decisions during Navigation Are Driven by a Small Subpopulation of Neurons in a Single Cortical Column of the Primary Somatosensory Cortex. [PDF]

J Neurosci
Armstrong AG, Vlasov Y.
europepmc   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

Males but not females report genital sensations evoked by fixed-parameter stimulation of somatosensory cortex. [PDF]

Brain
Proelss S, Tuncer MS, Heim C, Haynes JD, Vajkoczy P, Brecht M, Faust K.   +6 more
europepmc   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Temporal dynamics of somatosensory gating and facilitation in the primary somatosensory cortex during finger movements. [PDF]

Cereb Cortex
Wasaka T, Kida T.
europepmc   +1 more source

X-ray diffraction reveals alterations in mouse somatosensory cortex following sensory deprivation. [PDF]

J Neurosci Methods
Murokh S, Willerson E, Lazarev A, Lazarev P, Mourokh L, Brumberg JC.   +5 more
europepmc   +1 more source

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

The Journal of Physiology, EarlyView.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires, Matheus Naia Fioretto, Marcel Rodrigues Ferreira, Isabelle Tenori Ribeiro, Luísa Annibal Barata, Flávia Alessandra Maciel, Lucas Sobrinho Lemos, Renato Mattos, Luiz Marcos Frediane Portela, Patrick Vieira de Souza, Luisa Correia Gomes, Gustavo Monezzi Cordeiro, Wellerson Rodrigo Scarano, Patrícia Aline Boer, Jose Antonio Rocha Gontijo, Luis Antonio Justulin   +15 more
wiley   +1 more source

4‐Methylumbelliferone Restores Age‐Related Changes in Perineuronal Nets, Memory, and Neuroinflammation

Glia, Volume 74, Issue 12, December 2026.
Brain aging alters perineuronal nets and neuroinflammation. 4‐methylumbelliferone reversed these aging‐associated changes. 4‐methylumbelliferone reduced age‐associated cognitive decline. Six months of chronic oral treatment was well tolerated. ABSTRACT Aging‐associated cognitive decline is closely linked to dysregulated glial activity and chronic ...
Anda Cimpean, Jana Mizerakova, Noelia Martinez‐Varea, Dana Marekova, Lucia Machova Urdzikova, James W. Fawcett, Pavla Jendelova, Jessica C. F. Kwok   +7 more
wiley   +1 more source

Somatosensory evoked potentials and high-frequency oscillations after transcranial static magnetic stimulation over the primary somatosensory cortex. [PDF]

Sci Rep
Tanaka Y, Takahashi A, Ishizaka R, Minami K, Miyazaki T, Oguma K, Shimizume N, Ozaki I, Watanabe T.   +8 more
europepmc   +1 more source