Results 51 to 60 of about 70,598 (265)

Auditory input enhances somatosensory encoding and tactile goal-directed behavior

Nature Communications, 2021
Multi-sensory input can lead to dendritic integration at the single neuron level. Here the authors show that combined auditory and somatosensory input increases distal dendritic and somatic activity in layer 2/3 pyramidal neurons of the primary ...
L. Godenzini, D. Alwis, R. Guzulaitis, S. Honnuraiah, G. J. Stuart, L. M. Palmer   +5 more
doaj   +1 more source

Thickening in the somatosensory cortex of patients with migraine [PDF]

Neurology, 2007
To examine morphologic changes in the somatosensory cortex (SSC) of patients with migraine.Cortical thickness of the SSC of patients with migraine was measured in vivo and compared with age- and sex-matched healthy subjects. The cohort was composed of 24 patients with migraine, subdivided into 12 patients who had migraine with aura, 12 patients who had
Alexandre F M, DaSilva, Cristina, Granziera, Josh, Snyder, Nouchine, Hadjikhani   +3 more
openaire   +2 more sources

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

The effects of neck flexion on cerebral potentials evoked by visual, auditory and somatosensory stimuli and focal brain blood flow in related sensory cortices

Journal of Physiological Anthropology, 2012
Background A flexed neck posture leads to non-specific activation of the brain. Sensory evoked cerebral potentials and focal brain blood flow have been used to evaluate the activation of the sensory cortex.
Fujiwara Katsuo, Kunita Kenji, Kiyota Naoe, Mammadova Aida, Irei Mariko   +4 more
doaj   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Discriminability of Single and Multichannel Intracortical Microstimulation within Somatosensory Cortex

Frontiers in Bioengineering and Biotechnology, 2016
The addition of tactile and proprioceptive feedback to neuroprosthetic limbs is expected to significantly improve the control of these devices. Intracortical microstimulation (ICMS) of somatosensory cortex is a promising method of delivering this ...
Cynthia Kay Overstreet, Randall Blake Hellman, Ruben Ponce Wong, Veronica J. Santos, Stephen Helms Tillery   +4 more
doaj   +1 more source

Cortical Network Overconnectivity Relates to Sensory, Cognitive, and Social Dimensions in Young Children With Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT The heterogeneity in both the neurobiological mechanisms and the phenotypic presentations of autism spectrum disorder (ASD) poses a major challenge to clinical and translational research. Alterations in functional connectivity (FC) have been associated with ASD, yet it remains unclear whether and how divergent brain network properties may ...
Borja Rodríguez‐Herreros, Ahmad Mheich, Joana Maria Almeida Osório, Sonia Richetin, Vincent Junod, Lorène Arnold, Victoria Aeschbach, Lilia Nora Adamou, Katherina Gschwend, Laura Mendes, David Romascano, Paola Yu, Marine Jequier Gygax, Anne M. Maillard, Micah M. Murray, Mahmoud Hassan, Nadia Chabane   +16 more
wiley   +1 more source

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

Somatosensation Evoked by Cortical Surface Stimulation of the Human Primary Somatosensory Cortex

Frontiers in Neuroscience, 2019
Electrical stimulation of the primary somatosensory cortex using intracranial electrodes is crucial for the evocation of artificial somatosensations, typically tactile sensations associated with specific regions of the body, in brain-machine interface ...
St. Clair Kirin, St. Clair Kirin, Takufumi Yanagisawa, Takufumi Yanagisawa, Takufumi Yanagisawa, Satoru Oshino, Kohtaroh Edakawa, Masataka Tanaka, Haruhiko Kishima, Yukio Nishimura, Yukio Nishimura, Yukio Nishimura   +11 more
doaj   +1 more source