Results 71 to 80 of about 60,528 (335)

A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals

Advanced Science, EarlyView.
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang, Xue‐Jing Lu, Hui‐Juan Zhang, Zhao‐Xing Wei, Ya‐Zhuo Kong, Yi‐Heng Tu, Gian Domenico Iannetti, Li Hu   +7 more
wiley   +1 more source

Object-guided Spatial Attention in Touch: Holding the Same Object with Both Hands Delays Attentional Selection [PDF]

, 2009
Previous research has shown that attention to a specific location on a uniform visual object spreads throughout the entire object. Here we demonstrate that, similar to the visual system, spatial attention in touch can be object guided.
Bettina Forster, Driver J., Helge Gillmeister, Humphreys G. W., Julia Adler, Mangun G. R., Schicke T.   +6 more
core   +1 more source

Linking pain and the body: neural correlates of visually induced analgesia [PDF]

, 2012
The visual context of seeing the body can reduce the experience of acute pain, producing a multisensory analgesia. Here we investigated the neural correlates of this “visually induced analgesia” using fMRI.
,, Driver, J, Haggard, P, Iannetti, GD, Longo, MR, Mancini, F   +5 more
core   +2 more sources

Mesenchymal Stromal Cells Play an Analgesic Role Through a Npy2r Sensory Neuron‐Mediated Lung‐to‐Brain Axis

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSC) are considered a promising alternative for neuropathic pain (NP) treatment, but underlying mechanisms remain elusive. Huang et al. illustrate that a Npy2r sensory neuron‐related lung–brain axis contributes to MSC analgesia.
Jing Huang, Taihe Zhou, Yueming Sun, Yuanchen Ma, Yiwen Deng, Keyu Chen, Ruijie Li, Yuan Qiu, Tao Wang, Xiaoyong Chen, Li Huang, Lu Zhu, Xueyi Tu, Ying Wang, Zheming Liu, Rouchen Lin, Yunli Tong, Yuantao Li, Heshe Li, Lin Nie, Rui Fang, Jianqi Feng, Xuhong Wei, Xia Feng, Andy Peng Xiang, Xiaoran Zhang   +25 more
wiley   +1 more source

Motor and Somatosensory Evoked Potential Monitoring Without Wakeup Test during Scoliosis Surgery

Journal of Rawalpindi Medical College, 2019
Background: Available evidence suggests that Transcranial electric motor evoked potentials and somatosensory evoked potential are safe methods to check the integrity of the spinal cord during spine deformity correction surgery. We compare the efficacy of
Muhammad Kamran Ayoob, Ammar Dogar, Anum Hafeez, Abdullah Shah, Jamil Ahmed, Amer Aziz   +5 more
doaj  

Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge. [PDF]

, 2019
The mechanisms by which noninvasive vagal nerve stimulation (nVNS) affect central and peripheral neural circuits that subserve pain and autonomic physiology are not clear, and thus remain an area of intense investigation.
Baker, Dewleen G, Davis, Bryan, Huang, Charles, Huang, Mingxiong, Kimball, Donald, Lerman, Imanuel, Proudfoot, James, Rao, Ramesh, Simmons, Alan N, Simon, Bruce, Sorkin, Linda, Spadoni, Andrea, Strigo, Irina, Zhong, Edward   +13 more
core   +2 more sources

Advanced Image‐Guidance and Surgical‐Navigation Techniques for Real‐Time Visualized Surgery

Advanced Science, EarlyView.
This review comprehensively summarizes advances in surgical navigation, covering both established and emerging intraoperative imaging technologies. It highlights mechanisms, advantages, limitations, and clinical applications, while emphasizing interdisciplinary collaboration.
Xiaoxiao Fan, Xiaolong Liu, Qiming Xia, Guoqiao Chen, Jiaxi Cheng, Zhaoqi Shi, Yifeng Fang, Parikshit Asutosh Khadaroo, Jun Qian, Hui Lin   +9 more
wiley   +1 more source

Large-scale changes in cortical dynamics triggered by repetitive somatosensory electrical stimulation. [PDF]

, 2019
BackgroundRepetitive somatosensory electrical stimulation (SES) of forelimb peripheral nerves is a promising therapy; studies have shown that SES can improve motor function in stroke subjects with chronic deficits.
Burish, Mark J, Ganguly, Karunesh, Gulati, Tanuj, Hishinuma, April K   +3 more
core   +1 more source

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Intraoperative neurophysiological mapping & localization of posterior median sulcus during intramedullary spinal cord tumor resection_technical communication

Interdisciplinary Neurosurgery, 2019
Objectives: To assess orthodormic stimulation mapping technique for posterior median sulcus with some variation in parameters from that used in Simon study model.
Elamir Elsherif, MD, D.ABNM, Khaled AlMusrea, B.Med.Sc., MD, FRCSC, Yasser Orz, MD, PhD., Prof.   +2 more
doaj   +1 more source